2. Others Neuronal Signaling GPCR/G Protein
  3. Drug Derivative Serotonin Transporter Dopamine Transporter 5-HT Receptor
  4. EDMA hydrochloride

EDMA hydrochloride 是 MDMA 的衍生物。EDMA hydrochloride 是多种神经递质转运体的底物，包括 5-羟色胺转运体 (SERT)、多巴胺转运体 (DAT) 和去甲肾上腺素转运体 (NET)。EDMA hydrochloride 在 SERT 处具有 5-HT 释放活性，EC50 值为 117 nM，在 DAT 和 NET 处具有 MPP+ 释放活性，EC50 值为 597 和 325 nM 。

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EDMA hydrochloride

EDMA hydrochloride Chemical Structure

CAS No. : 2748304-41-6

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EDMA hydrochloride 相关抗体

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查看 5-HT Receptor 亚型特异性产品:

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5-HT Receptor 5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

EDMA hydrochloride is a derivative of MDMA. EDMA hydrochloride is a substrate for multiple neurotransmitter transporters, including serotonin transporter (SERT), dopamine transporter (DAT), and norepinephrine transporter (NET). EDMA hydrochloride has 5-HT releasing activity at SERT (EC50 = 117 nM) and MPP+ releasing activity at DAT (EC50 = 597 nM) and NET (EC50 = 325 nM)[1].

分子量

243.73

Formula

C12H18ClNO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

EDMA hydrochloride 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EDMA2748304-41-6Drug DerivativeSerotonin TransporterDopamine Transporter5-HT ReceptorDrug derivative5-HTTSERTSLC6A4DATSLC6A3Serotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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