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  3. Eritadenine

Eritadenine  (Synonyms: Lentinacin; D-Eritadenine; Lentysine)

目录号: HY-114866 纯度: 97.9%
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Eritadenine (D-Eritadenine) 是一种有效的 AdoHcyase 抑制剂,IC50 值为 7 nM。Eritadenine 也是一种无环糖腺苷类似物。Eritadenine 对小隐孢子虫 (Cryptosporidium parvum) 的生长有抑制作用,MIC50 为 3 μM。Eritadenine 可用于结直肠腺癌的研究。

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Eritadenine

Eritadenine Chemical Structure

CAS No. : 23918-98-1

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Eritadenine (D-Eritadenine) is a potent AdoHcyase inhibitor, with an IC50 value of 7 nM. Eritadenine is also an acyclic sugar adenosine analogue. Eritadenine exhibits an inhibitory effect on the growth of Cryptosporidium parvum, with a MIC50 of 3 μM. Eritadenine can be used in the research of colorectal adenocarcinoma[1][2].

IC50 & Target

SAHH[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Hepatocyte IC50
0.03 μM
Compound: eritadenine
Inhibition of S-adenosyl-L-homocysteine hydrolase in intact rat hepatocytes
Inhibition of S-adenosyl-L-homocysteine hydrolase in intact rat hepatocytes
[PMID: 19692248]
体外研究
(In Vitro)

D-Eritadenine (IC50 = 7 nM) 对 S-腺苷同型半胱氨酸水解酶 (AdoHcyase) 具有强效抑制作用[1]
D-Eritadenine (MIC50 = 3 μM) 对隐孢子虫 (Cryptosporidium parvum) 的生长具有抑制作用[2]
D-Eritadenine (1 mM; 48 h) 对未感染的 HCT-8 细胞表现出较低的细胞毒性,细胞存活率为 80%[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

253.21

Formula

C9H11N5O4

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: 97.9%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Eritadenine
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