2. Others Neuronal Signaling Membrane Transporter/Ion Channel Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds TRP Channel Endogenous Metabolite Calcium Channel
  4. Farnesyl pyrophosphate-d2 triammonium

Farnesyl pyrophosphate-d2 triammonium  (Synonyms: Farnesyl diphosphate-d2 triammonium)

目录号: HY-113037CS 纯度: 95.78%
COA 产品使用指南 技术支持

Farnesyl pyrophosphate-d2 (Farnesyl diphosphate-d2) triammonium 是氘代标记的 Farnesyl pyrophosphate triammonium (HY-113037C)。Farnesyl pyrophosphate ammonium 是甲羟戊酸 (MVA) 途径的代谢中间体。Farnesyl pyrophosphate ammonium 是一种 TRP Channel (TRPM2) 激动剂，可引发 Ca²⁺ 内流从而引发细胞死亡。Farnesyl pyrophosphate ammonium 是胆固醇合成、泛醌合成、蛋白质法尼基化修饰和香叶基-香叶基焦磷酸 (GGPP) 合成的关键分支底物。Farnesyl pyrophosphate ammonium 可用于脑缺血、神经退行性疾病、胰腺癌、炎症与自身免疫病等研究。

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Farnesyl pyrophosphate-d<sub>2</sub> triammonium

Farnesyl pyrophosphate-d2 triammonium Chemical Structure

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规格 价格 是否有货 数量
1 mg ￥4240
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Other Forms of Farnesyl pyrophosphate-d2 triammonium:

Farnesyl pyrophosphate-d2 triammonium 相关抗体

Top Publications Citing Use of Products

查看 TRP Channel 亚型特异性产品:

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TRPC TRPM TRPV TRPA TRPML

查看 Calcium Channel 亚型特异性产品:

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

  • 生物活性

  • 纯度 & 产品资料

生物活性

Farnesyl pyrophosphate-d2 (Farnesyl diphosphate-d2) triammonium is a deuterium labeled Farnesyl pyrophosphate triammonium (HY-113037C). Farnesyl pyrophosphate ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate ammonium is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate ammonium is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases.

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Farnesyl pyrophosphate-d2 triammonium 相关抗体:
分子量

435.43

Formula

C15H35D2N3O7P2
非标记 CAS
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料

Farnesyl pyrophosphate-d2 triammonium 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Farnesyl pyrophosphate-d2 triammoniumFarnesyl diphosphate-d2 triammoniumIsotope-Labeled CompoundsTRP ChannelEndogenous MetaboliteCalcium ChannelTransient receptor potential channelsCa2+ channelsCa channelsInhibitorinhibitorinhibit

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