2. Membrane Transporter/Ion Channel Neuronal Signaling Others Metabolic Enzyme/Protease
  3. TRP Channel Isotope-Labeled Compounds Endogenous Metabolite Calcium Channel
  4. Farnesyl pyrophosphate-d3

Farnesyl pyrophosphate-d3  (Synonyms: Farnesyl diphosphate-d3)

目录号: HY-113037S1
产品使用指南 技术支持

Farnesyl pyrophosphate-d3 (Farnesyl diphosphate-d3) 是氘代标记的 Farnesyl pyrophosphate (HY-113037B)。Farnesyl pyrophosphate 是甲羟戊酸 (MVA) 途径的代谢中间体。Farnesyl pyrophosphate 是一种 TRP Channel (TRPM2) 激动剂，可引发 Ca²⁺ 内流从而引发细胞死亡。Farnesyl pyrophosphate 是胆固醇合成、泛醌合成、蛋白质法尼基化修饰和香叶基-香叶基焦磷酸 (GGPP) 合成的关键分支底物。Farnesyl pyrophosphate 可用于脑缺血、神经退行性疾病、胰腺癌、炎症与自身免疫病等研究。

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Farnesyl pyrophosphate-d<sub>3</sub>

Farnesyl pyrophosphate-d3 Chemical Structure

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Other Forms of Farnesyl pyrophosphate-d3:

Farnesyl pyrophosphate-d3 相关抗体

Top Publications Citing Use of Products

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TRPC TRPM TRPV TRPA TRPML

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Farnesyl pyrophosphate-d3 (Farnesyl diphosphate-d3) is a deuterium labeled Farnesyl pyrophosphate (HY-113037B). Farnesyl pyrophosphate is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases.

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Farnesyl pyrophosphate-d3 相关抗体:
分子量

385.34

Formula

C15H25D3O7P2
非标记 CAS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Farnesyl pyrophosphate-d3 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Farnesyl pyrophosphate-d3Farnesyl diphosphate-d3TRP ChannelIsotope-Labeled CompoundsEndogenous MetaboliteCalcium ChannelTransient receptor potential channelsCa2+ channelsCa channelsInhibitorinhibitorinhibit

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