2. Metabolic Enzyme/Protease
  3. Fatty Acid Synthase (FASN) Cytochrome P450
  4. Floramanoside F

Floramanoside F 是一种黄酮醇苷类化合物。Floramanoside F 具有中等强度的自由基清除作用，SC₅₀ 为 25.1 μM。Floramanoside F 对醛糖还原酶的抑制活性较弱，IC₅₀ > 100 μM。Floramanoside F 与 1 型糖尿病肾病 (T1DN) 的关键靶点酶 (Fasn、Cyp2e1、Cyp4a32) 具有强结合力，能抑制脂质堆积和氧化应激，从而减轻肾脏炎症与纤维化。Floramanoside F 可用研究 1 型糖尿病肾病及糖尿病并发症。

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Floramanoside F

Floramanoside F Chemical Structure

CAS No. : 1487423-58-4

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Floramanoside F 相关抗体

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CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

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生物活性

Floramanoside F is a type of flavonol glycoside compound. Floramanoside F has a moderate free radical scavenging effect, with a SC₅₀ value of 25.1 μM. Floramanoside F has a relatively weak inhibitory activity on aldose reductase, with a IC₅₀ value greater than 100 μM. Floramanoside F has strong binding affinity with key target enzymes of type 1 diabetic nephropathy (T1DN) (Fasn, Cyp2e1, Cyp4a32), and can inhibit lipid accumulation and oxidative stress, thereby alleviating renal inflammation and fibrosis. Floramanoside F can be used to study type 1 diabetic nephropathy and diabetic complications[1][2].

分子量

522.41

Formula

C23H22O14
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Floramanoside F 相关分类

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Keywords:

Floramanoside F1487423-58-4Fatty Acid Synthase (FASN)Cytochrome P450CYPstype 1 diabetic nephropathyrenal injurydiabetic complicationsrat lens homogenatemouse modelsCyp4a3222-diphenyl-1-picrylhydrazyl free radicalfatty acid synthaseCyp2e1Huangkui capsuleInhibitorinhibitorinhibit

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