2. Metabolic Enzyme/Protease Anti-infection
  3. β-glucuronidase Influenza Virus RSV
  4. Forsyshiyanine A

Foryshiyanine A 是一种三萜生物碱。 Foryshiyanine A 具有抗炎活性，能够抑制大鼠多形核白细胞释放 β-葡萄糖醛酸酶 (β-glucuronidase)。 Foryshiyanine A 还具有抗病毒活性，对呼吸道合胞病毒 (RSV) 的 EC50 值为 4.5 μM，对甲型 H1N1 病毒的 IC50 值为 7.3 μM。 Foryshiyanine A 通过干扰病毒复制和进入来降低病毒载量。 Foryshiyanine A 可用于炎症和感染的研究。

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Forsyshiyanine A

Forsyshiyanine A Chemical Structure

CAS No. : 2767053-65-4

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Forsyshiyanine A 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Foryshiyanine A is a triterpenoid alkaloid. Foryshiyanine A possesses anti-inflammatory activity, inhibiting the release of β-glucuronidase from rat polymorphonuclear leukocytes. Foryshiyanine A exhibits antiviral activity, with an EC50 of 4.5 μM against respiratory syncytial virus (RSV) and an IC50 of 7.3 μM against influenza A virus (H1N1). Foryshiyanine A reduces viral load by disrupting viral replication and entry. Foryshiyanine A may be used for the researches of inflammation and infection[1][2].

体外研究
(In Vitro)

Forsyshiyanine A (Compound 1) (10 μM) 可抑制大鼠多形核白细胞释放 β-葡萄糖醛酸苷酶，抑制率为 54.5%[1]。
\r\nForsyshiyanine A 具有强效抗甲型流感病毒 (H1N1) 活性，IC50 值为 7.3 μM，且具有良好的抗呼吸道合胞病毒 (RSV) 活性，EC50 值为 4.5 μM[1]。
\r\nForsyshiyanine A (0.5-100 μg/mL) 对 MDCK 细胞无明显细胞毒性，细胞存活率保持在 80% 以上[1]。
\r\nForsyshiyanine A (50 μM) 对五种人类肿瘤细胞系 (A549 肺癌、A2058 黑色素瘤、HepG2 肝癌、MCF-7 乳腺癌、Mia PaCa-2 胰腺癌细胞) 无明显细胞毒性[2]。
\r\n

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Forsyshiyanine A 相关抗体:
分子量

259.39

Formula

C17H25NO
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Forsyshiyanine A 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Forsyshiyanine A2767053-65-4β-glucuronidaseInfluenza VirusRSVGUSBRespiratory syncytial virusMDCKA549 lung cancerA2058 melanomaHepG2 hepatomaMCF-7 breast cancerMia PaCa-2\npancreatic cancerInhibitorinhibitorinhibit

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