1. Anti-infection Metabolic Enzyme/Protease
  2. Fungal Endogenous Metabolite
  3. Fumitremorgin B

Fumitremorgin B 是一种震颤性真菌毒素。Fumitremorgin B 具有显着的抗真菌活性,MICs 值为 6.25-50 μg/mL。

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Fumitremorgin B

Fumitremorgin B Chemical Structure

CAS No. : 12626-17-4

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规格 价格 是否有货 数量
1 mg ¥4212
3 - 4 周
5 mg 询价

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Other Forms of Fumitremorgin B:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Fumitremorgin B is a tremorgenic mycotoxin. Fumitremorgin B exhibits significant antifungal activities, with MICs of 6.25-50 μg/mL[1][2][3].

IC50 & Target

fungal[3]

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HT-29 IC50
5 μM
Compound: 8; FTM-B
Cytotoxicity against human HT-29 cells
Cytotoxicity against human HT-29 cells
[PMID: 27865702]
HeLa IC50
5 μM
Compound: 8; FTM-B
Cytotoxicity against human HeLa cells
Cytotoxicity against human HeLa cells
[PMID: 27865702]
Jurkat IC50
5 μM
Compound: 8; FTM-B
Cytotoxicity against human Jurkat cells
Cytotoxicity against human Jurkat cells
[PMID: 27865702]
MCF7 IC50
5 μM
Compound: 8; FTM-B
Cytotoxicity against human MCF7 cells
Cytotoxicity against human MCF7 cells
[PMID: 27865702]
PC-3 IC50
43.36 μM
Compound: 574
Cytotoxicity against human PC-3 cells assessed as reduction in cell growth incubated for 48 hrs by CCK-8 assay
Cytotoxicity against human PC-3 cells assessed as reduction in cell growth incubated for 48 hrs by CCK-8 assay
[PMID: 38181652]
U-937 IC50
14.12 μM
Compound: 574
Cytotoxicity against human U-937 cells assessed as reduction in cell growth incubated for 48 hrs by CCK-8 assay
Cytotoxicity against human U-937 cells assessed as reduction in cell growth incubated for 48 hrs by CCK-8 assay
[PMID: 38181652]
体外研究
(In Vitro)

Fumitremorgin B (3 or 4 days) inhibits the proliferation of U937 and PC3 cells, with IC50 of 14.12 and 43.36 μM, respectively[2].
Fumitremorgin B exhibits antifungal activities against the phytopathogenic fungi B. cinerea, A. solani, A. alternata, C. gloeosporioides, F. solani, F. oxysporum f. sp. niveum, F. oxysporum f. sp. vasinfectum, and G. saubinettii, with MICs of 6.25-50 μg/mL[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

479.57

Formula

C27H33N3O5

CAS 号
性状

油状物

颜色

Off-white to light brown

中文名称

烟曲霉毒素B

结构分类
初始来源

fungus Aspergillus fumigatus

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥90.0%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Fumitremorgin B
目录号:
HY-117313
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