1. Gene
  2. Traf3ip2 - TRAF3 interacting protein 2 Gene

Traf3ip2 - TRAF3 interacting protein 2 Gene

种属: Mus musculus

同用名: Act1; CIKS

基因 ID: 103213 | 基因类型: protein coding

关于 Traf3ip2

功能概要

Enables signaling receptor binding activity and ubiquitin protein Ligase activity. Involved in several processes, including cell surface receptor signaling pathway; hematopoietic or lymphoid organ development; and leukocyte homeostasis. Acts upstream of or within B cell apoptotic process and humoral immune response. Is active in cytoplasmic vesicle and nucleus. Used to study Sjogren's syndrome; atopic dermatitis; and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in chronic mucocutaneous candidiasis and psoriasis 13. Orthologous to human TRAF3IP2 (TRAF3 interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Traf3ip2 基因产物(1)

mRNA Protein Name
NM_134000.3 NP_598761.2 E3 ubiquitin ligase TRAF3IP2
蛋白主名 其他名称

E3 ubiquitin ligase TRAF3IP2

adapter protein CIKS

E3 ubiquitin-protein ligase CIKS

connection to IKK and SAPK/JNK

nuclear factor NF-kappa-B activator 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Traf3ip2 NCBI NCBI:10758