1. Gene
  2. Adgrb1 - adhesion G protein-coupled receptor B1 Gene

Adgrb1 - adhesion G protein-coupled receptor B1 Gene

种属: Mus musculus

同用名: Bai1; mKIAA4089; B830018M07Rik

基因 ID: 107831 | 基因类型: protein coding

关于 Adgrb1

功能概要

Enables several functions, including PDZ domain binding activity; lipopolysaccharide binding activity; and phosphatidylserine binding activity. Involved in several processes, including negative regulation of protein metabolic process; phagocytosis; and positive regulation of myoblast fusion. Acts upstream of or within positive regulation of synapse assembly. Located in several cellular components, including focal adhesion; phagocytic cup; and postsynaptic density. Is expressed in several structures, including brain and reproductive system. Human ortholog(s) of this gene implicated in glioblastoma. Orthologous to human ADGRB1 (adhesion G protein-coupled receptor B1). [provided by Alliance of Genome Resources, Apr 2022]

Adgrb1 基因产物(2)

mRNA Protein Name
NM_001359759.1 NP_001346688.1 adhesion G protein-coupled receptor B1 isoform 2
NM_174991.3 NP_778156.2 adhesion G protein-coupled receptor B1 isoform 1precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables PDZ domain binding IPI
IPI: 通过物理相互作用推断
23782696 MGI
enables lipopolysaccharide binding IDA
IDA: 通过直接分析推断
21245295 MGI
enables phosphatidylserine binding IDA
IDA: 通过直接分析推断
17960134 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11245925 MGI
enables transmembrane signaling receptor activity IDA
IDA: 通过直接分析推断
17960134 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in defense response to Gram-negative bacterium IMP
IMP: 通过突变表型推断
21245295 MGI
involved in engulfment of apoptotic cell IDA
IDA: 通过直接分析推断
17960134 MGI
involved in negative regulation of protein catabolic process IMP
IMP: 通过突变表型推断
25751059 MGI
involved in negative regulation of protein ubiquitination IMP
IMP: 通过突变表型推断
25751059 MGI
involved in phagocytosis, engulfment IMP
IMP: 通过突变表型推断
26838550 MGI
involved in phagocytosis, recognition IMP
IMP: 通过突变表型推断
21245295 MGI
involved in positive regulation of myoblast fusion IMP
IMP: 通过突变表型推断
23615608 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: 通过直接分析推断
24613359 MGI
involved in regulation of synaptic plasticity IMP
IMP: 通过突变表型推断
25751059 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendrite IDA
IDA: 通过直接分析推断
20888903 MGI
located in focal adhesion IDA
IDA: 通过直接分析推断
20888903 MGI
located in phagocytic cup IDA
IDA: 通过直接分析推断
17960134 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
17960134 MGI
located in postsynaptic density IDA
IDA: 通过直接分析推断
23595754 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

adhesion G protein-coupled receptor B1

brain-specific angiogenesis inhibitor 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adgrb1 NCBI NCBI:575