1. Gene
  2. Chn1 - chimerin 1 Gene

Chn1 - chimerin 1 Gene

种属: Mus musculus

同用名: ARHGAP2; 0610007I19Rik; 0710001E19Rik; 1700112L09Rik; 2900046J01Rik

基因 ID: 108699 | 基因类型: protein coding

关于 Chn1

功能概要

Enables Ephrin Receptor binding activity. Involved in several processes, including Ephrin Receptor signaling pathway; motor neuron axon guidance; and regulation of GTPase activity. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Used to study Duane retraction syndrome. Human ortholog(s) of this gene implicated in Duane retraction syndrome. Orthologous to human CHN1 (chimerin 1). [provided by Alliance of Genome Resources, Apr 2022]

Chn1 基因产物(5)

mRNA Protein Name
NM_001113246.2 NP_001106717.2 N-chimaerin isoform 3
NM_001166603.1 NP_001160075.1 N-chimaerin isoform 4
NM_001166604.1 NP_001160076.1 N-chimaerin isoform 5
NM_029716.3 NP_083992.1 N-chimaerin isoform 2
NM_175752.3 NP_786928.2 N-chimaerin isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ephrin receptor binding IPI
IPI: 通过物理相互作用推断
17719550 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17719550 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ephrin receptor signaling pathway IMP
IMP: 通过突变表型推断
17785183 MGI
involved in motor neuron axon guidance IMP
IMP: 通过突变表型推断
17785183 MGI
involved in regulation of GTPase activity IDA
IDA: 通过直接分析推断
17719550 MGI
involved in regulation of axonogenesis IDA
IDA: 通过直接分析推断
17719550 MGI
involved in regulation of axonogenesis IMP
IMP: 通过突变表型推断
17785183 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

N-chimaerin

A-chimaerin

N-chimerin

NC

alpha-chimerin

alpha1 chimaerin

alpha2 chimaerin

alpha3-chimerin

chimaerin

chimerin (chimaerin) 1

rho GTPase-activating protein 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chn1 NCBI NCBI:1123