1. Gene
  2. Pmch - pro-melanin-concentrating hormone Gene

Pmch - pro-melanin-concentrating hormone Gene

种属: Mus musculus

同用名: A230109K23Rik

基因 ID: 110312 | 基因类型: protein coding

关于 Pmch

功能概要

This gene encodes a preproprotein that is cleaved to produce three mature peptides: melanin concentrating hormone, neuropeptide-glutamic acid-isoleucine (NEI), and neuropeptide-glycine-glutamic acid (NGE). The proprotein is processed differently depending on the tissue where it is expressed. Melanin concentrating hormone is involved in the regulation of food intake, energy homeostasis, and sleep-wake behavior. Disruption of this gene is associated with resistance to diet-induced obesity. [provided by RefSeq, May 2013]

Pmch 基因产物(1)

mRNA Protein Name
NM_029971.2 NP_084247.1 pro-MCH preproprotein
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in feeding behavior IMP
IMP: 通过突变表型推断
11867747 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
8724342 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

pro-MCH

neuropeptide-glutamic acid-isoleucine (NEI)

neuropeptide-glycine-glutamic acid (NGE)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pmch NCBI NCBI:5367