2. Gene
  3. Abcb7 - ATP-binding cassette, sub-family B (MDR/TAP), member 7 Gene

Abcb7 - ATP-binding cassette, sub-family B (MDR/TAP), member 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Abc7

基因 ID: 11306 | 基因类型: protein coding

关于 Abcb7

功能概要

Predicted to enable ABC-type iron-sulfur cluster transporter activity and protein homodimerization activity. Involved in iron-sulfur cluster assembly; positive regulation of heme biosynthetic process; and positive regulation of iron-sulfur cluster assembly. Acts upstream of or within cellular iron ion homeostasis. Located in mitochondrial inner membrane. Is expressed in several structures, including adrenal gland; central nervous system; gut; hemolymphoid system gland; and retina. Human ortholog(s) of this gene implicated in X-linked sideroblastic anemia with ataxia. Orthologous to human ABCB7 (ATP binding cassette subfamily B member 7). [provided by Alliance of Genome Resources, Apr 2022]

Abcb7 基因产物(1)

mRNA Protein Name
NM_009592.1 NP_033722.1 iron-sulfur clusters transporter ABCB7, mitochondrial
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
30765471 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within intracellular iron ion homeostasis IMP
IMP: 通过突变表型推断
16424901 MGI
involved in intracellular iron ion homeostasis IMP
IMP: 通过突变表型推断
30765471 MGI
involved in iron-sulfur cluster assembly IMP
IMP: 通过突变表型推断
30765471 MGI
involved in positive regulation of heme biosynthetic process IMP
IMP: 通过突变表型推断
30765471 MGI
involved in positive regulation of iron-sulfur cluster assembly IMP
IMP: 通过突变表型推断
16467350 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

iron-sulfur clusters transporter ABCB7, mitochondrial

ABC transporter 7 protein

ATP-binding cassette 7

ATP-binding cassette sub-family B member 7, mitochondrial

ATP-binding cassette transporter 7

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00054 ABCB7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21467 Abcb7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27985 Abcb7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Abcb7 NCBI NCBI:22
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