1. Gene
  2. Tdg - thymine-DNA glycosylase Gene

Tdg - thymine-DNA glycosylase Gene

种属: Rattus norvegicus

基因 ID: 114521 | 基因类型: protein coding

关于 Tdg

功能概要

Enables DNA-binding transcription factor binding activity and protein domain specific binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human TDG (thymine DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

Tdg 基因产物(2)

mRNA Protein Name
NM_001388503.1 NP_001375432.1 G/T mismatch-specific thymine DNA glycosylase isoform 1
NM_053729.2 NP_446181.2 G/T mismatch-specific thymine DNA glycosylase isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
11438542 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
11438542 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11438542 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
18945672 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

G/T mismatch-specific thymine DNA glycosylase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tdg NCBI NCBI:6996
Mus musculus Tdg NCBI NCBI:21665