2. Gene
  3. Adra2a - adrenergic receptor, alpha 2a Gene

Adra2a - adrenergic receptor, alpha 2a Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Adra-2; Adra-2a; alpha2A; alpha2-C10; alpha2A-AR; alpha(2A)AR

基因 ID: 11551 | 基因类型: protein coding

关于 Adra2a

功能概要

Enables Adrenergic Receptor activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within G protein-coupled receptor signaling pathway and fear response. Is active in dopaminergic synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb segment; and sensory organ. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and type 2 diabetes mellitus. Orthologous to human ADRA2A (adrenoceptor alpha 2A). [provided by Alliance of Genome Resources, Apr 2022]

Adra2a 基因产物(1)

mRNA Protein Name
NM_007417.5 NP_031443.4 alpha-2A adrenergic receptor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables adrenergic receptor activity IMP
IMP: 通过突变表型推断
15218143 MGI
enables alpha2-adrenergic receptor activity IMP
IMP: 通过突变表型推断
17992256 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9235896 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
15218143 MGI
acts upstream of or within fear response IMP
IMP: 通过突变表型推断
15105370 MGI
involved in negative regulation of insulin secretion IDA
IDA: 通过直接分析推断
1898674 MGI
involved in negative regulation of insulin secretion IMP
IMP: 通过突变表型推断
1898674 MGI
involved in presynaptic modulation of chemical synaptic transmission EXP
EXP: 通过实验结果推断
11927164 MGI
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
11927164 MGI
involved in presynaptic modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
11927164 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in dopaminergic synapse EXP
EXP: 通过实验结果推断
11927164 MGI
is active in dopaminergic synapse IDA
IDA: 通过直接分析推断
11927164 MGI
is active in dopaminergic synapse IMP
IMP: 通过突变表型推断
11927164 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

alpha-2A adrenergic receptor

alpha-2A adrenoceptor

alpha-2A adrenoreceptor

alpha-2AAR

alpha2A-adrenergic receptor

subtype alpha2-C10

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N8728 Aposcopolamine 98.44% 否
HY-163694 ADRA2A antagonist 1 Antagonist 98.02% 否
HY-145700 UCSF648 / 否
HY-RS00411 ADRA2A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-134125 Yohimbic acid ethyl ester Antagonist / 否
HY-RS17718 Adra2a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24183 Adra2a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adra2a NCBI NCBI:150
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