2. Gene
  3. Amelx - amelogenin, X-linked Gene

Amelx - amelogenin, X-linked Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Amg; ALGN; AMGL; AMGX; Amel; LRAP; Rgsc888

基因 ID: 11704 | 基因类型: protein coding

关于 Amelx

功能概要

Enables several functions, including growth factor activity; hydroxyapatite binding activity; and metal ion binding activity. Involved in cell adhesion; enamel mineralization; and regulation of cell population proliferation. Acts upstream of or within odontogenesis of dentin-containing tooth. Located in basement membrane; cell surface; and supramolecular complex. Part of protein-containing complex. Is expressed in several structures, including connective tissue; eye; jaw; nervous system; and skeleton. Used to study amelogenesis imperfecta type 1E. Human ortholog(s) of this gene implicated in amelogenesis imperfecta and amelogenesis imperfecta type 1E. Orthologous to several human genes including AMELX (amelogenin X-linked). [provided by Alliance of Genome Resources, Apr 2022]

Amelx 基因产物(3)

mRNA Protein Name
NM_001081978.2 NP_001075447.1 amelogenin, X isoform isoform 1 precursor
NM_001290371.1 NP_001277300.1 amelogenin, X isoform isoform 3 precursor
NM_009666.4 NP_033796.1 amelogenin, X isoform isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
19086270 MGI
enables growth factor activity IMP
IMP: 通过突变表型推断
16674693 MGI
enables hydroxyapatite binding IDA
IDA: 通过直接分析推断
11852235 MGI
enables identical protein binding IDA
IDA: 通过直接分析推断
23896516 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
9041053 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11063033 MGI
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
19086270 MGI
enables sodium ion binding IDA
IDA: 通过直接分析推断
19086270 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in amelogenesis IDA
IDA: 通过直接分析推断
26403673 MGI
involved in cell adhesion IMP
IMP: 通过突变表型推断
16674693 MGI
involved in enamel mineralization IDA
IDA: 通过直接分析推断
26403673 MGI
involved in odontogenesis of dentin-containing tooth IEP
IEP: 通过表达模式推断
16674683 MGI
involved in regulation of cell population proliferation IMP
IMP: 通过突变表型推断
16674693 MGI
involved in tooth mineralization IMP
IMP: 通过突变表型推断
11406633 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basement membrane IDA
IDA: 通过直接分析推断
18757743 MGI
located in cell surface IMP
IMP: 通过突变表型推断
16674683 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
19086270 MGI
located in supramolecular complex IDA
IDA: 通过直接分析推断
20304108 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

amelogenin, X isoform

amelogenin X chromosome

enamel matrix protein

leucine-rich amelogenin peptide

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00647 AMELX Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19982 Amelx Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26486 Amelx Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Amelx NCBI NCBI:265
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