2. Gene
  3. Ptpn2 - protein tyrosine phosphatase, non-receptor type 2 Gene

Ptpn2 - protein tyrosine phosphatase, non-receptor type 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 117063 | 基因类型: protein coding

关于 Ptpn2

功能概要

Enables non-membrane spanning protein tyrosine Phosphatase activity. Predicted to be involved in several processes, including hemopoiesis; negative regulation of leukocyte differentiation; and regulation of signal transduction. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II and protein dephosphorylation. Predicted to be located in several cellular components, including endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; and nucleoplasm. Predicted to colocalize with plasma membrane. Orthologous to human PTPN2 (protein tyrosine Phosphatase non-receptor type 2). [provided by Alliance of Genome Resources, Apr 2022]

Ptpn2 基因产物(2)

mRNA Protein Name
NM_001414231.1 NP_001401160.1 tyrosine-protein phosphatase non-receptor type 2 isoform 2
NM_053990.3 NP_446442.1 tyrosine-protein phosphatase non-receptor type 2 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables non-membrane spanning protein tyrosine phosphatase activity IDA
IDA: 通过直接分析推断
8534367 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tyrosine-protein phosphatase non-receptor type 2

protein-tyrosine phosphatase PTP-S

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-145923 Osunprotafib Inhibitor 99.43% Phase 1
Pre-clinical Phase
生物活性分子 (19)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148691 PROTAC PTPN2 degrader-1 Degrader 95.01% 否
HY-153446 Tegeprotafib Inhibitor 99.30% 否
HY-153638 PTPN2/1-IN-2 Antagonist 99.56% 否
HY-162428 PTPN2/1-IN-3 Inhibitor 99.89% 否
HY-149760 PVD-06 Inhibitor / 否
HY-RS11421 PTPN2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-145923B Osunprotafib hydrochloride Inhibitor / 否
HY-153938 PROTAC PTPN2 degrader-2 / 否
HY-153938A PROTAC PTPN2 degrader-2 TFA / 否
HY-156606 Anticancer agent 142 Inhibitor / 否
HY-156607 Anticancer agent 143 Inhibitor / 否
HY-156608 Anticancer agent 144 Inhibitor / 否
HY-163596 PTPN2-IN-1 Inhibitor / 否
HY-168691 PTPN2 ligand 1 / 否
HY-178716 PTPN2/1-IN-4 / 否
HY-179380 PTPN2-IN-2 / 否
HY-181255 PTPN2-IN-3 Inhibitor / 否
HY-RS16588 Ptpn2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23023 Ptpn2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptpn2 NCBI NCBI:5771
Mus musculus Ptpn2 NCBI NCBI:19255
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