2. Gene
  3. Slc25a4 - solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 Gene

Slc25a4 - solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ant1; mANC1

基因 ID: 11739 | 基因类型: protein coding

关于 Slc25a4

功能概要

Enables ATP:ADP antiporter activity; Oxidative Phosphorylation uncoupler activity; and proton transmembrane transporter activity. Involved in several processes, including adenine nucleotide transport; positive regulation of mitophagy; and regulation of mitochondrial membrane permeability. Acts upstream of or within apoptotic mitochondrial changes. Located in mitochondrial inner membrane and myelin sheath. Part of mitochondrial permeability transition pore complex. Is expressed in embryo and liver. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); mitochondrial DNA depletion syndrome (multiple); and mitochondrial myopathy (multiple). Orthologous to human SLC25A4 (solute carrier family 25 member 4). [provided by Alliance of Genome Resources, Apr 2022]

Slc25a4 基因产物(1)

mRNA Protein Name
NM_007450.5 NP_031476.3 ADP/ATP translocase 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP:ADP antiporter activity IDA
IDA: 通过直接分析推断
31341297 MGI
enables ATP:ADP antiporter activity IMP
IMP: 通过突变表型推断
31618756 MGI
enables oxidative phosphorylation uncoupler activity IDA
IDA: 通过直接分析推断
31341297 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11809823 MGI
enables proton transmembrane transporter activity IDA
IDA: 通过直接分析推断
31341297 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adaptive thermogenesis IMP
IMP: 通过突变表型推断
31341297 MGI
acts upstream of or within apoptotic mitochondrial changes IGI
IGI: 通过遗传相互作用推断
18350175 MGI
involved in mitochondrial ADP transmembrane transport IDA
IDA: 通过直接分析推断
31341297 MGI
involved in mitochondrial ADP transmembrane transport IMP
IMP: 通过突变表型推断
31618756 MGI
involved in mitochondrial ATP transmembrane transport IDA
IDA: 通过直接分析推断
31341297 MGI
involved in mitochondrial ATP transmembrane transport IMP
IMP: 通过突变表型推断
31618756 MGI
involved in positive regulation of mitophagy IDA
IDA: 通过直接分析推断
31618756 MGI
involved in regulation of mitochondrial membrane permeability IMP
IMP: 通过突变表型推断
31489369 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of mitochondrial permeability transition pore complex IMP
IMP: 通过突变表型推断
31489369 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ADP/ATP translocase 1

ADP,ATP carrier protein 1

ADP,ATP carrier protein, heart/skeletal muscle

ANT 1

adenine nucleotide translocase-1

adenine nucleotide translocator 1, skeletal muscle

solute carrier family 25 member 4

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13122 SLC25A4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22037 Slc25a4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28554 Slc25a4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc25a4 NCBI NCBI:291
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z