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  2. Avpr2 - arginine vasopressin receptor 2 Gene

Avpr2 - arginine vasopressin receptor 2 Gene

中文名称:精氨酸加压素受体 2

种属: Mus musculus

同用名: DI1; DIR; ND1; V2R; ADHR; VPV2R

基因 ID: 12000 | 基因类型: protein coding

关于 Avpr2

Chromosome X: 72,935,708-72,939,108 forward strand.GRCm39:CM001013.3

This gene has 4 transcripts (splice variants), 233 orthologues, 16 paralogues and is associated with 12 phenotypes. Biased expression in kidney adult (RPKM 17.2), thymus adult (RPKM 4.6) and 1 other tissue.

功能概要

该基因编码 G 蛋白偶联受体 1 家族和加压素/催产素受体亚家族的成员。编码的蛋白质是一种精氨酸加压素受体,当受到刺激时,它会激活 Gs 蛋白/腺苷酸环化酶信号级联,并参与水和电解质的稳态。可变剪接导致多个转录本变体。 [RefSeq 提供,2013 年 1 月]

This gene encodes a member of the G-protein coupled receptor 1 family and the vasopressin/Oxytocin Receptor subfamily. The encoded protein is an arginine Vasopressin Receptor which, when stimulated, activates the Gs protein/adenylyl cyclase signaling cascade and is involved in water and electrolyte homeostasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Avpr2 基因产物(3)

mRNA Protein Name
NM_019404.2 NP_062277.1 vasopressin V2 receptor isoform a
NM_001276298.1 NP_001263227.1 vasopressin V2 receptor isoform b
NM_001276299.1 NP_001263228.1 vasopressin V2 receptor isoform c

Avpr2 蛋白结构

7tmA_V2R

7tmA_V2R: cd15388 (37 - 325)

7tmA_V2R

7tmA_V2R: cd15388 (38 - 64)

7tmA_V2R

7tmA_V2R: cd15388 (73 - 100)

7tmA_V2R

7tmA_V2R: cd15388 (111 - 141)

7tmA_V2R

7tmA_V2R: cd15388 (154 - 175)

7tmA_V2R

7tmA_V2R: cd15388 (201 - 230)

7tmA_V2R

7tmA_V2R: cd15388 (263 - 293)

7tmA_V2R

7tmA_V2R: cd15388 (303 - 325)

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  • 100
  • 200
  • 300
  • 371 a.a.
蛋白主名 其他名称

vasopressin V2 receptor

antidiuretic hormone receptor

nephrogenic diabetes insipidus

renal-type arginine vasopressin receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Avpr2 NCBI NCBI:554