2. Gene
  3. Bmp10 - bone morphogenetic protein 10 Gene

Bmp10 - bone morphogenetic protein 10 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: b2b2711Clo

基因 ID: 12154 | 基因类型: protein coding

关于 Bmp10

功能概要

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of Smad Family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. Homozygous knockout mice for this gene exhibit impaired heart development and embryonic lethality. [provided by RefSeq, Aug 2016]

Bmp10 基因产物(1)

mRNA Protein Name
NM_009756.3 NP_033886.2 bone morphogenetic protein 10 preproprotein
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in BMP signaling pathway IDA
IDA: 通过直接分析推断
16798733 MGI
involved in adult heart development IMP
IMP: 通过突变表型推断
16798733 MGI
involved in atrial cardiac muscle tissue morphogenesis IEP
IEP: 通过表达模式推断
10072785 MGI
involved in cardiac muscle cell proliferation IMP
IMP: 通过突变表型推断
15073151 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
15073151 MGI
involved in heart trabecula formation IMP
IMP: 通过突变表型推断
15073151 MGI
acts upstream of or within kidney development IMP
IMP: 通过突变表型推断
27002738 MGI
involved in negative regulation of cardiac muscle hypertrophy IMP
IMP: 通过突变表型推断
16798733 MGI
involved in positive regulation of SMAD protein signal transduction IDA
IDA: 通过直接分析推断
16798733 MGI
involved in positive regulation of cardiac muscle cell proliferation IMP
IMP: 通过突变表型推断
17336907 MGI
involved in positive regulation of cartilage development IDA
IDA: 通过直接分析推断
19956691 MGI
involved in positive regulation of cell proliferation involved in heart morphogenesis IGI
IGI: 通过遗传相互作用推断
17336907 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: 通过直接分析推断
22783020 MGI
involved in ventricular cardiac muscle cell development IDA
IDA: 通过直接分析推断
16798733 MGI
involved in ventricular cardiac muscle tissue morphogenesis IMP
IMP: 通过突变表型推断
15073151 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

bone morphogenetic protein 10

BMP-10

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01534 BMP10 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19175 Bmp10 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25664 Bmp10 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bmp10 NCBI NCBI:27302
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z