1. Gene
  2. Ccne2 - cyclin E2 Gene

Ccne2 - cyclin E2 Gene

种属: Mus musculus

基因 ID: 12448 | 基因类型: protein coding

关于 Ccne2

功能概要

Enables cyclin-dependent protein serine/threonine kinase regulator activity. Acts upstream of or within several processes, including DNA metabolic process; homologous chromosome pairing at meiosis; and regulation of protein localization. Part of cyclin E2-CDK2 complex. Is expressed in several structures, including cerebral cortex and genitourinary system. Human ortholog(s) of this gene implicated in castration-resistant prostate carcinoma. Orthologous to human CCNE2 (cyclin E2). [provided by Alliance of Genome Resources, Apr 2022]

Ccne2 基因产物(3)

mRNA Protein Name
NM_001037134.2 NP_001032211.1 G1/S-specific cyclin-E2 isoform 1
NM_001282943.1 NP_001269872.1 G1/S-specific cyclin-E2 isoform 1
NM_009830.3 NP_033960.1 G1/S-specific cyclin-E2 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cyclin-dependent protein serine/threonine kinase regulator activity IDA
IDA: 通过直接分析推断
9840927 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within DNA replication initiation IMP
IMP: 通过突变表型推断
12941272 MGI
acts upstream of or within chromosome organization involved in meiotic cell cycle IGI
IGI: 通过遗传相互作用推断
24586195 MGI
acts upstream of or within homologous chromosome pairing at meiosis IGI
IGI: 通过遗传相互作用推断
24586195 MGI
acts upstream of or within regulation of cell cycle IDA
IDA: 通过直接分析推断
9840927 MGI
acts upstream of or within regulation of protein localization IGI
IGI: 通过遗传相互作用推断
24586195 MGI
acts upstream of or within telomere maintenance IGI
IGI: 通过遗传相互作用推断
24586195 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of cyclin E2-CDK2 complex IDA
IDA: 通过直接分析推断
7739547 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

G1/S-specific cyclin-E2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ccne2 NCBI NCBI:9134