1. Gene
  2. Clk2 - CDC-like kinase 2 Gene

Clk2 - CDC-like kinase 2 Gene

种属: Mus musculus

基因 ID: 12748 | 基因类型: protein coding

关于 Clk2

功能概要

Enables protein serine/threonine kinase activity and protein tyrosine kinase activity. Involved in negative regulation of gluconeogenesis and protein autophosphorylation. Acts upstream of or within peptidyl-tyrosine phosphorylation and response to retinoic acid. Located in nucleus. Is expressed in several structures, including brain; genitourinary system; liver; retina; and thyroid gland. Orthologous to human CLK2 (CDC like kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Clk2 基因产物(2)

mRNA Protein Name
NM_001163432.2 NP_001156904.1 dual specificity protein kinase CLK2 isoform 2
NM_007712.4 NP_031738.2 dual specificity protein kinase CLK2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
9307018 MGI
enables protein tyrosine kinase activity IDA
IDA: 通过直接分析推断
9307018 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of gluconeogenesis IMP
IMP: 通过突变表型推断
20074525 MGI
acts upstream of or within peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
9307018 MGI
acts upstream of or within protein autophosphorylation IDA
IDA: 通过直接分析推断
9307018 MGI
involved in protein autophosphorylation IDA
IDA: 通过直接分析推断
9852100 MGI
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
20074525 MGI
acts upstream of or within response to retinoic acid IDA
IDA: 通过直接分析推断
18400104 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
9307018 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

dual specificity protein kinase CLK2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Clk2 NCBI NCBI:1196