2. Gene
  3. Creb1 - cAMP responsive element binding protein 1 Gene

Creb1 - cAMP responsive element binding protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Creb; Creb-1; 2310001E10Rik; 3526402H21Rik

基因 ID: 12912 | 基因类型: protein coding

关于 Creb1

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and cAMP response element binding activity. Involved in several processes, including cellular response to retinoic acid; positive regulation of biosynthetic process; and protein stabilization. Acts upstream of or within several processes, including animal organ development; cellular response to hepatocyte growth factor stimulus; and cellular response to Leukemia Inhibitory Factor. Located in chromatin and nucleus. Part of ATF4-CREB1 transcription factor complex. Is expressed in several structures, including genitourinary system; limb; maxillary process; peripheral nervous system ganglion; and telencephalon. Orthologous to human CREB1 (cAMP responsive element binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Creb1 基因产物(3)

mRNA Protein Name
NM_001037726.1 NP_001032815.1 cyclic AMP-responsive element-binding protein 1 isoform C
NM_009952.2 NP_034082.1 cyclic AMP-responsive element-binding protein 1 isoform B
NM_133828.2 NP_598589.2 cyclic AMP-responsive element-binding protein 1 isoform A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
11354513 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
20876357 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
12220541 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
28763438 MGI
enables cAMP response element binding IDA
IDA: 通过直接分析推断
23729669 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17550780 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15030764 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within axonogenesis IMP
IMP: 通过突变表型推断
11988169 MGI
involved in cellular response to growth factor stimulus IDA
IDA: 通过直接分析推断
16427017 MGI
acts upstream of or within cellular response to hepatocyte growth factor stimulus IDA
IDA: 通过直接分析推断
21072211 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
involved in cellular response to retinoic acid IMP
IMP: 通过突变表型推断
20876357 MGI
acts upstream of or within cellular response to zinc ion IDA
IDA: 通过直接分析推断
23716681 MGI
involved in circadian rhythm IDA
IDA: 通过直接分析推断
20852621 MGI
acts upstream of hormone secretion IMP
IMP: 通过突变表型推断
16141355 MGI
acts upstream of or within lactation IMP
IMP: 通过突变表型推断
16141355 MGI
acts upstream of or within lung epithelium development IMP
IMP: 通过突变表型推断
21408140 MGI
acts upstream of or within lung saccule development IMP
IMP: 通过突变表型推断
21408140 MGI
acts upstream of or within mammary gland development IMP
IMP: 通过突变表型推断
16141355 MGI
acts upstream of or within memory IMP
IMP: 通过突变表型推断
23223304 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
30566056 MGI
acts upstream of osteoclast differentiation IDA
IDA: 通过直接分析推断
23395171 MGI
acts upstream of or within pituitary gland development IMP
IMP: 通过突变表型推断
16141355 MGI
involved in positive regulation of DNA-templated transcription IGI
IGI: 通过遗传相互作用推断
21728997 MGI
acts upstream of or within positive regulation of cardiac muscle tissue development IMP
IMP: 通过突变表型推断
24364879 MGI
involved in positive regulation of fat cell differentiation IGI
IGI: 通过遗传相互作用推断
21728997 MGI
acts upstream of or within positive regulation of hormone secretion IMP
IMP: 通过突变表型推断
16141355 MGI
involved in positive regulation of lipid biosynthetic process IGI
IGI: 通过遗传相互作用推断
21728997 MGI
acts upstream of or within positive regulation of multicellular organism growth IMP
IMP: 通过突变表型推断
16141355 MGI
acts upstream of or within positive regulation of osteoclast differentiation IDA
IDA: 通过直接分析推断
23395171 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
18252718 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
20852621 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
20876357 MGI
involved in protein stabilization IMP
IMP: 通过突变表型推断
21728997 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12220541 MGI
acts upstream of or within regulation of cell size IGI
IGI: 通过遗传相互作用推断
12015964 MGI
involved in regulation of testosterone biosynthetic process IDA
IDA: 通过直接分析推断
21333348 MGI
involved in regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12871976 MGI
involved in response to glucagon IMP
IMP: 通过突变表型推断
20852621 MGI
acts upstream of or within response to xenobiotic stimulus IDA
IDA: 通过直接分析推断
9098922 MGI
acts upstream of or within secretory granule organization IMP
IMP: 通过突变表型推断
21408140 MGI
acts upstream of or within type I pneumocyte differentiation IMP
IMP: 通过突变表型推断
21408140 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of ATF4-CREB1 transcription factor complex IDA
IDA: 通过直接分析推断
12871976 MGI
part of RNA polymerase II transcription regulator complex IPI
IPI: 通过物理相互作用推断
12871976 MGI
located in chromatin IDA
IDA: 通过直接分析推断
16427017 MGI
located in chromatin IMP
IMP: 通过突变表型推断
20876357 MGI
is active in nucleus IDA
IDA: 通过直接分析推断
21728997 MGI
located in nucleus IDA
IDA: 通过直接分析推断
7565774 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
11354513 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cyclic AMP-responsive element-binding protein 1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03148 CREB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-P4497 Prolylserine Inhibitor / 否
HY-RS18270 Creb1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24748 Creb1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Creb1 NCBI NCBI:1385
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