2. Gene
  3. Asap1 - ArfGAP with SH3 domain, ankyrin repeat and PH domain1 Gene

Asap1 - ArfGAP with SH3 domain, ankyrin repeat and PH domain1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PAP; s19; DEF-1; Ddef1; mKIAA1249

基因 ID: 13196 | 基因类型: protein coding

关于 Asap1

功能概要

Enables GTPase activator activity; SH3 domain binding activity; and phospholipid binding activity. Acts upstream of or within negative regulation of dendritic spine development; positive regulation of membrane tubulation; and positive regulation of podosome assembly. Located in cell projection membrane; dendritic spine; and podosome. Is active in cytosol and plasma membrane. Is expressed in several structures, including gonad; limb; long bone; perichondrium; and thoracic duct. Orthologous to human ASAP1 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 1). [provided by Alliance of Genome Resources, Apr 2022]

Asap1 基因产物(6)

mRNA Protein Name
NM_001276461.2 NP_001263390.1 arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform b
NM_001276462.2 NP_001263391.1 arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform c
NM_001276463.2 NP_001263392.1 arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform d
NM_001276467.2 NP_001263396.1 arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform e
NM_001411185.1 NP_001398114.1 arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform f
NM_010026.4 NP_034156.2 arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase activator activity IDA
IDA: 通过直接分析推断
10734117 MGI
enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
IDA: 通过直接分析推断
10734117 MGI
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: 通过直接分析推断
10734117 MGI
enables phosphatidylserine binding IDA
IDA: 通过直接分析推断
16431365 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9819391 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of dendritic spine development IDA
IDA: 通过直接分析推断
23050017 MGI
acts upstream of or within positive regulation of membrane tubulation IDA
IDA: 通过直接分析推断
16431365 MGI
involved in regulation of postsynapse organization IDA
IDA: 通过直接分析推断
23050017 MGI
involved in regulation of postsynapse organization IMP
IMP: 通过突变表型推断
23050017 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendritic spine IDA
IDA: 通过直接分析推断
23050017 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
23050017 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
23050017 MGI
located in podosome IDA
IDA: 通过直接分析推断
21352810 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein

130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein

ADP-ribosylation factor-directed GTPase-activating protein 1

ARF GTPase-activat

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01055 ASAP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20858 Asap1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27373 Asap1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Asap1 NCBI NCBI:50807
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