1. Gene
  2. Dlx3 - distal-less homeobox 3 Gene

Dlx3 - distal-less homeobox 3 Gene

种属: Mus musculus

同用名: Dlx-3

基因 ID: 13393 | 基因类型: protein coding

关于 Dlx3

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and chromatin binding activity. Acts upstream of or within several processes, including odontoblast differentiation; odontogenesis of dentin-containing tooth; and placenta development. Located in nucleus. Is expressed in several structures, including brain; branchial arch; genitourinary system; jaw; and sensory organ. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 4 and trichodontoosseous syndrome. Orthologous to human DLX3 (distal-less homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Dlx3 基因产物(1)

mRNA Protein Name
NM_010055.4 NP_034185.1 homeobox protein DLX-3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
22351765 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
18684741 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
22351765 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
35922041 MGI
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
23371388 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in BMP signaling pathway IMP
IMP: 通过突变表型推断
18684741 MGI
involved in Wnt signaling pathway IMP
IMP: 通过突变表型推断
18684741 MGI
acts upstream of or within blood vessel development IMP
IMP: 通过突变表型推断
9874789 MGI
involved in gene expression IMP
IMP: 通过突变表型推断
18684741 MGI
involved in hair cell differentiation IMP
IMP: 通过突变表型推断
18684741 MGI
involved in hair cycle IMP
IMP: 通过突变表型推断
18684741 MGI
involved in hair follicle cell proliferation IMP
IMP: 通过突变表型推断
18684741 MGI
involved in hair follicle development IMP
IMP: 通过突变表型推断
18684741 MGI
involved in hair follicle morphogenesis IMP
IMP: 通过突变表型推断
18684741 MGI
acts upstream of or within odontoblast differentiation IMP
IMP: 通过突变表型推断
22351765 MGI
involved in odontoblast differentiation IMP
IMP: 通过突变表型推断
22351765 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IMP
IMP: 通过突变表型推断
22351765 MGI
acts upstream of or within placenta development IMP
IMP: 通过突变表型推断
9874789 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
23371388 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
35922041 MGI
located in nucleus IDA
IDA: 通过直接分析推断
19796622 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

homeobox protein DLX-3

DII C

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dlx3 NCBI NCBI:1747