2. Gene
  3. Dpp6 - dipeptidylpeptidase 6 Gene

Dpp6 - dipeptidylpeptidase 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Rw; Dpp-6; Peplb; D5Buc3; D5Buc4; D5Buc5; DPP VI; Gm1377; In(5)6H-p; B930011P16Rik

基因 ID: 13483 | 基因类型: protein coding

关于 Dpp6

功能概要

Enables Potassium Channel regulator activity. Involved in protein localization to plasma membrane and regulation of potassium ion transmembrane transport. Acts upstream of or within neuronal action potential and positive regulation of potassium ion transmembrane transport. Located in plasma membrane. Part of voltage-gated Potassium Channel complex. Is expressed in several structures, including 1st branchial arch; alimentary system; central nervous system; intervertebral disc; and nose. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; autosomal dominant non-syndromic intellectual disability 33; and spinal muscular atrophy. Orthologous to human DPP6 (Dipeptidyl Peptidase like 6). [provided by Alliance of Genome Resources, Apr 2022]

Dpp6 基因产物(4)

mRNA Protein Name
NM_001136060.2 NP_001129532.1 dipeptidyl aminopeptidase-like protein 6 isoform 1
NM_001198886.1 NP_001185815.1 dipeptidyl aminopeptidase-like protein 6 isoform 4
NM_010075.2 NP_034205.1 dipeptidyl aminopeptidase-like protein 6 isoform 2
NM_207282.3 NP_997165.2 dipeptidyl aminopeptidase-like protein 6 isoform 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables potassium channel regulator activity IDA
IDA: 通过直接分析推断
22311982 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
24225951 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of establishment of localization in cell IMP
IMP: 通过突变表型推断
21943606 MGI
acts upstream of or within neuronal action potential IMP
IMP: 通过突变表型推断
20573902 MGI
acts upstream of or within positive regulation of potassium ion transmembrane transport IMP
IMP: 通过突变表型推断
21943606 MGI
acts upstream of potassium ion transmembrane transport IMP
IMP: 通过突变表型推断
21943606 MGI
involved in protein localization to plasma membrane IDA
IDA: 通过直接分析推断
22311982 MGI
acts upstream of or within regulation of membrane potential IMP
IMP: 通过突变表型推断
20573902 MGI
involved in regulation of postsynaptic membrane potential IDA
IDA: 通过直接分析推断
21943606 MGI
involved in regulation of postsynaptic membrane potential IEP
IEP: 通过表达模式推断
21943606 MGI
involved in regulation of postsynaptic membrane potential IMP
IMP: 通过突变表型推断
21943606 MGI
involved in regulation of potassium ion transmembrane transport IDA
IDA: 通过直接分析推断
22311982 MGI
acts upstream of or within regulation of potassium ion transmembrane transport IGI
IGI: 通过遗传相互作用推断
24225951 MGI
acts upstream of or within regulation of potassium ion transport IMP
IMP: 通过突变表型推断
20573902 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
24225951 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
22311982 MGI
is active in synapse IDA
IDA: 通过直接分析推断
23912628 MGI
part of voltage-gated potassium channel complex IDA
IDA: 通过直接分析推断
19713751 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dipeptidyl aminopeptidase-like protein 6

DPPX

dipeptidyl aminopeptidase-related protein

dipeptidyl peptidase IV-like protein

dipeptidyl peptidase VI

dipeptidylpeptidase VI

inversion, Chr 5, Harwell 6, proximal

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03966 DPP6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21327 Dpp6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27846 Dpp6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dpp6 NCBI NCBI:1804
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