2. Gene
  3. Dmtn - dematin actin binding protein Gene

Dmtn - dematin actin binding protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Epb49; Epb4.9; dematin

基因 ID: 13829 | 基因类型: protein coding

关于 Dmtn

功能概要

Enables protein self-association. Involved in several processes, including calcium-mediated signaling; negative regulation of protein phosphorylation; and regulation of cell-substrate adhesion. Located in several cellular components, including cortical cytoskeleton; perinuclear region of cytoplasm; and postsynaptic density. Is expressed in central nervous system; dorsal root ganglion; liver lobe; and sensory organ. Orthologous to human DMTN (dematin actin binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Dmtn 基因产物(13)

mRNA Protein Name
NM_001252662.1 NP_001239591.1 dematin isoform 1
NM_001252663.1 NP_001239592.1 dematin isoform 2
NM_001252664.1 NP_001239593.1 dematin isoform 3
NM_001252665.1 NP_001239594.1 dematin isoform 4
NM_001252666.1 NP_001239595.1 dematin isoform 4
NM_001360024.1 NP_001346953.1 dematin isoform 1
NM_001360025.1 NP_001346954.1 dematin isoform 1
NM_001360026.1 NP_001346955.1 dematin isoform 1
NM_001360027.1 NP_001346956.1 dematin isoform 2
NM_001360028.1 NP_001346957.1 dematin isoform 3
NM_001360029.1 NP_001346958.1 dematin isoform 4
NM_001360030.1 NP_001346959.1 dematin isoform 3
NM_013514.4 NP_038542.1 dematin isoform 2
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin cytoskeleton organization IMP
IMP: 通过突变表型推断
12011427 MGI
involved in endoplasmic reticulum tubular network organization IMP
IMP: 通过突变表型推断
23060452 MGI
involved in erythrocyte development IMP
IMP: 通过突变表型推断
12011427 MGI
involved in negative regulation of cell-substrate adhesion IMP
IMP: 通过突变表型推断
18505823 MGI
involved in negative regulation of focal adhesion assembly IMP
IMP: 通过突变表型推断
18505823 MGI
involved in negative regulation of peptidyl-serine phosphorylation IMP
IMP: 通过突变表型推断
18505823 MGI
involved in negative regulation of peptidyl-threonine phosphorylation IMP
IMP: 通过突变表型推断
18505823 MGI
involved in negative regulation of peptidyl-tyrosine phosphorylation IMP
IMP: 通过突变表型推断
18505823 MGI
involved in negative regulation of protein targeting to membrane IMP
IMP: 通过突变表型推断
18505823 MGI
involved in negative regulation of substrate adhesion-dependent cell spreading IMP
IMP: 通过突变表型推断
18505823 MGI
involved in positive regulation of fibroblast migration IDA
IDA: 通过直接分析推断
18505823 MGI
involved in positive regulation of wound healing IMP
IMP: 通过突变表型推断
18505823 MGI
involved in protein-containing complex assembly IDA
IDA: 通过直接分析推断
12011427 MGI
involved in regulation of cell shape IDA
IDA: 通过直接分析推断
18505823 MGI
involved in smooth endoplasmic reticulum calcium ion homeostasis IMP
IMP: 通过突变表型推断
23060452 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell projection membrane IDA
IDA: 通过直接分析推断
18505823 MGI
located in cortical cytoskeleton IDA
IDA: 通过直接分析推断
18723693 MGI
located in cytosol IDA
IDA: 通过直接分析推断
18505823 MGI
located in membrane IDA
IDA: 通过直接分析推断
18723693 MGI
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
18505823 MGI
located in postsynaptic density IDA
IDA: 通过直接分析推断
17114649 MGI
is active in synapse EXP
EXP: 通过实验结果推断
34269176 MGI
is active in synapse IDA
IDA: 通过直接分析推断
34269176 MGI
is active in synapse IMP
IMP: 通过突变表型推断
34269176 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dematin

erythrocyte membrane protein band 4.9

erythrocyte protein band 4.9

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03834 DMTN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22141 Dmtn Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dmtn NCBI NCBI:2039
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