1. Gene
  2. Eps15 - epidermal growth factor receptor pathway substrate 15 Gene

Eps15 - epidermal growth factor receptor pathway substrate 15 Gene

种属: Mus musculus

同用名: 2410112D09Rik

基因 ID: 13858 | 基因类型: protein coding

关于 Eps15

功能概要

Enables identical protein binding activity. Acts upstream of or within regulation of protein localization. Located in ciliary membrane; clathrin-coated pit; and clathrin-coated vesicle. Part of AP-2 adaptor complex. Is expressed in several structures, including adrenal gland; alimentary system; heart; metanephros; and nervous system. Orthologous to human EPS15 (epidermal growth factor receptor pathway substrate 15). [provided by Alliance of Genome Resources, Apr 2022]

Eps15 基因产物(2)

mRNA Protein Name
NM_001159964.1 NP_001153436.1 epidermal growth factor receptor substrate 15 isoform B
NM_007943.3 NP_031969.1 epidermal growth factor receptor substrate 15 isoform A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
18154663 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9446614 MGI
enables ubiquitin binding IDA
IDA: 通过直接分析推断
15383614 MGI
enables ubiquitin binding IMP
IMP: 通过突变表型推断
15383614 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within regulation of protein localization IMP
IMP: 通过突变表型推断
17868307 MGI
involved in ubiquitin-dependent endocytosis IMP
IMP: 通过突变表型推断
15383614 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of AP-2 adaptor complex IDA
IDA: 通过直接分析推断
17626015 MGI
located in ciliary membrane IDA
IDA: 通过直接分析推断
20427320 MGI
part of clathrin coat of coated pit IDA
IDA: 通过直接分析推断
18434600 MGI
located in clathrin-coated pit IDA
IDA: 通过直接分析推断
20427320 MGI
located in clathrin-coated vesicle IDA
IDA: 通过直接分析推断
17626015 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
17626015 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

epidermal growth factor receptor substrate 15

epidermal growth factor pathway substrate 15

protein AF-1p

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Eps15 NCBI NCBI:2060