1. Gene
  2. F8 - coagulation factor VIII Gene

F8 - coagulation factor VIII Gene

种属: Mus musculus

同用名: Cf8; Cf-8; FVIII

基因 ID: 14069 | 基因类型: protein coding

关于 F8

功能概要

Predicted to enable copper ion binding activity and oxidoreductase activity. Predicted to be involved in blood coagulation, intrinsic pathway. Predicted to act upstream of or within acute-phase response and hemostasis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and liver and biliary system. Used to study Factor VIII deficiency. Human ortholog(s) of this gene implicated in Factor VIII deficiency. Orthologous to human F8 (coagulation Factor VIII). [provided by Alliance of Genome Resources, Apr 2022]

F8 基因产物(3)

mRNA Protein Name
NM_001161373.1 NP_001154845.1 coagulation factor VIII isoform 2 precursor
NM_001161374.1 NP_001154846.1 coagulation factor VIII isoform 3 precursor
NM_007977.2 NP_032003.2 coagulation factor VIII isoform 1 precursor
蛋白主名 其他名称

coagulation factor VIII

Factor VIII

procoagulant component

直系同源

种属 基因名 来源 基因 ID
Homo sapiens F8 NCBI NCBI:2157
Felis catus F8 NCBI NCBI:101092751
Macaca fascicularis F8 NCBI NCBI:102125498
Rattus norvegicus F8 NCBI NCBI:302470