2. Gene
  3. Fcgr1 - Fc receptor, IgG, high affinity I Gene

Fcgr1 - Fc receptor, IgG, high affinity I Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CD64; IGGHAFC; FcgammaRI

基因 ID: 14129 | 基因类型: protein coding

关于 Fcgr1

功能概要

Enables IgG binding activity and IgG receptor activity. Acts upstream of or within several processes, including antibody-dependent cellular cytotoxicity; endocytosis; and positive regulation of hypersensitivity. Located in external side of plasma membrane. Is expressed in liver. Orthologous to several human genes including FCGR1A (Fc gamma receptor Ia). [provided by Alliance of Genome Resources, Apr 2022]

Fcgr1 基因产物(1)

mRNA Protein Name
NM_010186.5 NP_034316.1 high affinity immunoglobulin gamma Fc receptor I precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables IgG binding IDA
IDA: 通过直接分析推断
9551950 MGI
enables IgG binding IMP
IMP: 通过突变表型推断
11911823 MGI
enables IgG receptor activity IMP
IMP: 通过突变表型推断
9551950 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within antibody-dependent cellular cytotoxicity IMP
IMP: 通过突变表型推断
11911823 MGI
acts upstream of or within antigen processing and presentation of exogenous antigen IMP
IMP: 通过突变表型推断
11911823 MGI
acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class I IMP
IMP: 通过突变表型推断
11911824 MGI
acts upstream of or within cell surface receptor signaling pathway IMP
IMP: 通过突变表型推断
9551950 MGI
acts upstream of or within defense response to bacterium IMP
IMP: 通过突变表型推断
11911824 MGI
acts upstream of or within phagocytosis, engulfment IMP
IMP: 通过突变表型推断
9551950 MGI
acts upstream of or within phagocytosis, recognition IMP
IMP: 通过突变表型推断
9551950 MGI
acts upstream of or within positive regulation of phagocytosis IMP
IMP: 通过突变表型推断
9551950 MGI
acts upstream of or within positive regulation of type III hypersensitivity IMP
IMP: 通过突变表型推断
11911823 MGI
acts upstream of or within positive regulation of type IIa hypersensitivity IMP
IMP: 通过突变表型推断
11911824 MGI
acts upstream of or within receptor-mediated endocytosis IMP
IMP: 通过突变表型推断
11911823 MGI
acts upstream of or within regulation of immune response IMP
IMP: 通过突变表型推断
11911823 MGI
acts upstream of or within response to bacterium IMP
IMP: 通过突变表型推断
16836651 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
11911823 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

high affinity immunoglobulin gamma Fc receptor I

IgG high affinity Fc receptor

fc-gamma RI

fcRI

igG Fc receptor I

重组 Fcgr1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72714 CD64 Protein, Mouse (HEK293, His) P26151 (E25-P297) ≥95%
HY-P72927 CD64 Protein, Mouse (HEK293, His-Avi) P26151 (E25-P297) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04827 FCGR1A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24478 Fcgr1a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris Fcgr1 NCBI
Macaca fascicularis Fcgr1 NCBI
Leporidae Fcgr1 NCBI
Rattus norvegicus Fcgr1 NCBI
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