2. Gene
  3. Foxm1 - forkhead box M1 Gene

Foxm1 - forkhead box M1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: WIN; Mpm2; Fkh16; Foxm1b; HFH-11B; MPHOSPH2

基因 ID: 14235 | 基因类型: protein coding

关于 Foxm1

功能概要

Enables transcription cis-regulatory region binding activity. Involved in DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; positive regulation of double-strand break repair; and positive regulation of transcription, DNA-templated. Acts upstream of or within several processes, including liver development; positive regulation of transcription by RNA polymerase II; and vasculogenesis. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study hepatocellular carcinoma; lung cancer; and type 2 diabetes mellitus. Orthologous to human FOXM1 (forkhead box M1). [provided by Alliance of Genome Resources, Apr 2022]

Foxm1 基因产物(1)

mRNA Protein Name
NM_008021.4 NP_032047.4 forkhead box protein M1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10523841 MGI
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
17261592 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator IMP
IMP: 通过突变表型推断
17101782 MGI
acts upstream of cell population proliferation IMP
IMP: 通过突变表型推断
15817462 MGI
acts upstream of or within liver development IMP
IMP: 通过突变表型推断
15531365 MGI
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
17101782 MGI
involved in positive regulation of double-strand break repair IMP
IMP: 通过突变表型推断
17101782 MGI
acts upstream of or within positive regulation of stem cell proliferation IMP
IMP: 通过突变表型推断
15817462 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15817462 MGI
acts upstream of or within regulation of cell population proliferation IMP
IMP: 通过突变表型推断
15531365 MGI
acts upstream of stem cell proliferation IMP
IMP: 通过突变表型推断
15817462 MGI
acts upstream of or within vasculogenesis IMP
IMP: 通过突变表型推断
15817462 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
17261592 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

forkhead box protein M1

forkhead homolog 16

trident

winged-helix transcription factor Trident

相关产品

Pre-clinical Phase
生物活性分子 (24)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-B0990 Thiostrepton Inhibitor 99.80% 否
HY-112721 FDI-6 Inhibitor 99.60% 否
HY-19979 RCM-1 Inhibitor 98.56% 否
HY-158420 STL001 Inducer 99.81% 否
HY-153916 TCRS-417 99.13% 否
HY-148530 YX-2-107 Degrader 98.60% 否
HY-117522 Sepin-1 Inhibitor 99.29% 否
HY-151986 FOXM1-IN-1 Inhibitor 99.86% 否
HY-149145 Ena15 ≥99.0% 否
HY-RS05064 FOXM1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-P10553 ARF(26–44), cell-permeable / 否
HY-P11228 FPP29 99.20% 否
HY-P1687 Siomycin A / 否
HY-170944 BAG3/HSP70-IN-1 / 否
HY-112509 STL427944 Inhibitor / 否
HY-150038 NOSH-aspirin / 否
HY-156609 FOXM1-IN-2 Inhibitor / 否
HY-161617 LASSBio-2052 / 否
HY-170552 KC12 Inhibitor / 否
HY-178462 Hsp70/FoxM1-IN-1 Inhibitor / 否
HY-181076 FOXM1-IN-3 / 否
HY-P11494 AWWNTEW / 否
HY-RS16641 Foxm1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23075 Foxm1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Foxm1 NCBI NCBI:2305
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