1. Gene
  2. Dtx1 - deltex 1, E3 ubiquitin ligase Gene

Dtx1 - deltex 1, E3 ubiquitin ligase Gene

种属: Mus musculus

同用名: Fxit1; mKIAA4160

基因 ID: 14357 | 基因类型: protein coding

关于 Dtx1

功能概要

Predicted to enable Notch binding activity; ubiquitin protein Ligase activity; and ubiquitin protein Ligase binding activity. Acts upstream of or within several processes, including Notch signaling pathway; cellular response to leukemia inhibitory factor; and negative regulation of T cell differentiation. Predicted to be located in cytosol and nuclear body. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Orthologous to human DTX1 (deltex E3 ubiquitin Ligase 1). [provided by Alliance of Genome Resources, Apr 2022]

Dtx1 基因产物(1)

mRNA Protein Name
NM_008052.3 NP_032078.2 E3 ubiquitin-protein ligase DTX1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11226752 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Notch signaling pathway IDA
IDA: 通过直接分析推断
11226752 MGI
acts upstream of or within Notch signaling pathway IMP
IMP: 通过突变表型推断
15965470 MGI
acts upstream of T cell differentiation IDA
IDA: 通过直接分析推断
12794108 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
acts upstream of or within glial cell differentiation IMP
IMP: 通过突变表型推断
15965470 MGI
acts upstream of or within negative regulation of T cell differentiation IDA
IDA: 通过直接分析推断
12794108 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase DTX1

FXI-T1

RING-type E3 ubiquitin transferase DTX1

deltex 1 homolog

deltex1

fractionated x-irradiation induced transcript 1

mDTX1

protein deltex-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dtx1 NCBI NCBI:1840