1. Gene
  2. Gap43 - growth associated protein 43 Gene

Gap43 - growth associated protein 43 Gene

种属: Mus musculus

同用名: B-50; Basp2; GAP-43

基因 ID: 14432 | 基因类型: protein coding

关于 Gap43

功能概要

Predicted to enable Calmodulin binding activity and phospholipid binding activity. Acts upstream of or within axon choice point recognition; cell fate commitment; and glial cell differentiation. Located in several cellular components, including axon; plasma membrane; and postsynaptic density. Is expressed in several structures, including alimentary system; future brain; genitourinary system; nervous system; and sensory organ. Orthologous to human GAP43 (growth associated protein 43). [provided by Alliance of Genome Resources, Apr 2022]

Gap43 基因产物(1)

mRNA Protein Name
NM_008083.2 NP_032109.1 neuromodulin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23462742 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within astrocyte differentiation IMP
IMP: 通过突变表型推断
15234344 MGI
acts upstream of or within axon choice point recognition IMP
IMP: 通过突变表型推断
7859286 MGI
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
10662636 MGI
acts upstream of or within cell fate commitment IMP
IMP: 通过突变表型推断
15234344 MGI
acts upstream of or within radial glial cell differentiation IMP
IMP: 通过突变表型推断
15234344 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
10482234 MGI
located in cell periphery IDA
IDA: 通过直接分析推断
21752992 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
24582971 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
16892058 MGI
located in postsynaptic density IDA
IDA: 通过直接分析推断
17114649 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

neuromodulin

axonal membrane protein GAP-43

brain abundant, membrane attached signal protein 2

calmodulin-binding protein P-57

growth accentuating protein 43

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gap43 NCBI NCBI:2596