Glul - glutamate-ammonia ligase (glutamine synthetase) Gene

种属: Mus musculus

同用名: GS; Glns

关于 Glul

功能概要

Predicted to enable several functions, including anion binding activity; dynein light chain binding activity; and metal ion binding activity. Involved in regulation of endothelial cell migration and regulation of sprouting angiogenesis. Acts upstream of or within cellular response to starvation and response to glucose. Located in cell body; cytoplasm; and glial cell projection. Is expressed in several structures, including alimentary system; central nervous system; respiratory system; sensory organ; and urinary system. Used to study temporal lobe epilepsy. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; and temporal lobe epilepsy. Orthologous to human GLUL (glutamate-ammonia Ligase). [provided by Alliance of Genome Resources, Apr 2022]