1. Gene
  2. Gp1ba - glycoprotein 1b, alpha polypeptide Gene

Gp1ba - glycoprotein 1b, alpha polypeptide Gene

种属: Mus musculus

同用名: GPIba; GPIbalpha; GP-Ib alpha

基因 ID: 14723 | 基因类型: protein coding

关于 Gp1ba

功能概要

Acts upstream of or within blood coagulation and cell morphogenesis. Colocalizes with anchored component of external side of plasma membrane. Is expressed in dorsal root ganglion; embryo; liver; and spinal cord. Used to study Bernard-Soulier syndrome. Human ortholog(s) of this gene implicated in Bernard-Soulier syndrome; Bernard-Soulier syndrome type A2; myocardial infarction; non-arteritic anterior ischemic optic neuropathy; and platelet-type bleeding disorder 3. Orthologous to human GP1BA (glycoprotein Ib platelet subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Gp1ba 基因产物(1)

mRNA Protein Name
NM_010326.3 NP_034456.2 platelet glycoprotein Ib alpha chain precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in blood coagulation IDA
IDA: 通过直接分析推断
18187573 MGI
acts upstream of or within blood coagulation IMP
IMP: 通过突变表型推断
20650879 MGI
acts upstream of or within cell morphogenesis IMP
IMP: 通过突变表型推断
10706630 MGI
acts upstream of or within hemostasis IMP
IMP: 通过突变表型推断
10706630 MGI
involved in megakaryocyte development IMP
IMP: 通过突变表型推断
18187573 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
28576878 MGI
colocalizes with external side of plasma membrane IDA
IDA: 通过直接分析推断
19443707 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

platelet glycoprotein Ib alpha chain

glycoprotein Ibalpha

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gp1ba NCBI NCBI:2811