1. Gene
  2. Gpc1 - glypican 1 Gene

Gpc1 - glypican 1 Gene

种属: Mus musculus

基因 ID: 14733 | 基因类型: protein coding

关于 Gpc1

功能概要

Enables Fibroblast Growth Factor binding activity and laminin binding activity. Involved in negative regulation of Fibroblast Growth Factor receptor signaling pathway. Acts upstream of or within positive regulation of skeletal muscle cell differentiation. Located in extracellular matrix; membrane raft; and synapse. Is expressed in several structures, including alimentary system; limb; metanephros; musculoskeletal system; and nervous system. Orthologous to human GPC1 (glypican 1). [provided by Alliance of Genome Resources, Apr 2022]

Gpc1 基因产物(1)

mRNA Protein Name
NM_016696.5 NP_057905.1 glypican-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fibroblast growth factor binding IDA
IDA: 通过直接分析推断
20100867 MGI
enables laminin binding IDA
IDA: 通过直接分析推断
20100867 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of fibroblast growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
20100867 MGI
involved in positive regulation of skeletal muscle cell differentiation IEP
IEP: 通过表达模式推断
20100867 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular matrix IDA
IDA: 通过直接分析推断
20100867 MGI
located in membrane raft IDA
IDA: 通过直接分析推断
20100867 MGI
is active in synapse EXP
EXP: 通过实验结果推断
16452087 MGI
is active in synapse IDA
IDA: 通过直接分析推断
16452087 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

glypican-1

重组 Gpc1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70928 Glypican-1/GPC1 Protein, Mouse (HEK293, His) Q9QZF2 (D24-S529) ≥ 95%, as determined by reducing SDS-PAGE.

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gpc1 NCBI NCBI:2817