2. Gene
  3. Id3 - inhibitor of DNA binding 3 Gene

Id3 - inhibitor of DNA binding 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Idb3; Hlh462; bHLHb25

基因 ID: 15903 | 基因类型: protein coding

关于 Id3

功能概要

Enables leptomycin B binding activity; protein domain specific binding activity; and transcription regulator inhibitor activity. Involved in negative regulation of myoblast differentiation; negative regulation of transcription, DNA-templated; and positive regulation of gene expression. Acts upstream of or within several processes, including animal organ development; cellular response to leptomycin B; and negative regulation of macromolecule metabolic process. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; limb; metanephros; and sensory organ. Used to study Sjogren's syndrome. Orthologous to human ID3 (inhibitor of DNA binding 3, HLH protein). [provided by Alliance of Genome Resources, Apr 2022]

Id3 基因产物(1)

mRNA Protein Name
NM_008321.2 NP_032347.1 DNA-binding protein inhibitor ID-3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables bHLH transcription factor binding IPI
IPI: 通过物理相互作用推断
8759016 MGI
enables leptomycin B binding IDA
IDA: 通过直接分析推断
23523789 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
8759016 MGI
enables protein domain specific binding IDA
IDA: 通过直接分析推断
2000388 MGI
enables transcription regulator inhibitor activity IDA
IDA: 通过直接分析推断
17681138 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leptomycin B IDA
IDA: 通过直接分析推断
23523789 MGI
involved in central nervous system development IEP
IEP: 通过表达模式推断
7655079 MGI
involved in circadian rhythm IEP
IEP: 通过表达模式推断
19217292 MGI
acts upstream of or within epithelial cell differentiation IDA
IDA: 通过直接分析推断
16407553 MGI
acts upstream of or within heart development IGI
IGI: 通过遗传相互作用推断
15472070 MGI
involved in metanephros development IEP
IEP: 通过表达模式推断
7655079 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
19217292 MGI
acts upstream of or within negative regulation of gene expression IDA
IDA: 通过直接分析推断
23523789 MGI
involved in negative regulation of myoblast differentiation IMP
IMP: 通过突变表型推断
23824195 MGI
acts upstream of or within negative regulation of osteoblast differentiation IGI
IGI: 通过遗传相互作用推断
15161906 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
2000388 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
19217292 MGI
involved in notochord development IEP
IEP: 通过表达模式推断
7655079 MGI
involved in odontogenesis IEP
IEP: 通过表达模式推断
7655079 MGI
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
17681138 MGI
involved in positive regulation of gene expression IGI
IGI: 通过遗传相互作用推断
17681138 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
8083744 MGI
located in nucleus IMP
IMP: 通过突变表型推断
23523789 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA-binding protein inhibitor ID-3

ID-like protein inhibitor HLH 462

inhibitor of differentiation 3

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-124697 BMP signaling agonist sb4 Agonist 99.98% 否
HY-110245 DMH2 Inducer 99.84% 否
HY-RS06524 ID3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-143623S Neo Spiramycin I-d3 / 否
HY-155705 BMP agonist 1 / 否
HY-181116 Anticancer agent 298 / 否
HY-RS17523 Id3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23980 Id3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Id3 NCBI NCBI:3399
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