2. Gene
  3. Inpp5d - inositol polyphosphate-5-phosphatase D Gene

Inpp5d - inositol polyphosphate-5-phosphatase D Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: SHIP; SHIP1; SHIP-1; s-SHIP; SIP-145; p150Ship

基因 ID: 16331 | 基因类型: protein coding

关于 Inpp5d

功能概要

Enables Phosphatase activity and protein domain specific binding activity. Acts upstream of or within several processes, including negative regulation of B cell proliferation; negative regulation of bone resorption; and regulation of hemopoiesis. Predicted to be located in actin filament; cortical cytoskeleton; and cytosol. Predicted to colocalize with plasma membrane. Is expressed in several structures, including integumental system; nervous system; respiratory system; skeleton; and spleen. Used to study Paget's disease of bone and systemic lupus erythematosus. Orthologous to human INPP5D (inositol polyphosphate-5-phosphatase D). [provided by Alliance of Genome Resources, Apr 2022]

Inpp5d 基因产物(6)

mRNA Protein Name
NM_001110192.2 NP_001103662.1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 2
NM_001110193.2 NP_001103663.1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 3
NM_010566.3 NP_034696.2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 1
NM_001110192.2 NP_001103662.1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 2
NM_001110193.2 NP_001103663.1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 3
NM_010566.3 NP_034696.2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10068665 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within determination of adult lifespan IMP
IMP: 通过突变表型推断
9620849 MGI
acts upstream of or within immunoglobulin mediated immune response IMP
IMP: 通过突变表型推断
10704460 MGI
acts upstream of or within intracellular signal transduction IMP
IMP: 通过突变表型推断
10704460 MGI
acts upstream of or within negative regulation of B cell activation IMP
IMP: 通过突变表型推断
10704460 MGI
acts upstream of or within negative regulation of B cell proliferation IMP
IMP: 通过突变表型推断
10704460 MGI
acts upstream of or within negative regulation of bone resorption IMP
IMP: 通过突变表型推断
12161749 MGI
acts upstream of or within negative regulation of granulocyte differentiation IMP
IMP: 通过突变表型推断
9620849 MGI
acts upstream of or within negative regulation of immune response IMP
IMP: 通过突变表型推断
10704460 MGI
acts upstream of or within negative regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
12161749 MGI
acts upstream of or within negative regulation of monocyte differentiation IMP
IMP: 通过突变表型推断
9620849 MGI
acts upstream of or within negative regulation of neutrophil differentiation IMP
IMP: 通过突变表型推断
9620849 MGI
acts upstream of or within negative regulation of osteoclast differentiation IMP
IMP: 通过突变表型推断
12161749 MGI
acts upstream of or within negative regulation of signal transduction IMP
IMP: 通过突变表型推断
9620849 MGI
acts upstream of or within positive regulation of B cell differentiation IMP
IMP: 通过突变表型推断
9620849 MGI
acts upstream of or within positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
12161749 MGI
acts upstream of or within positive regulation of erythrocyte differentiation IMP
IMP: 通过突变表型推断
9620849 MGI
acts upstream of or within positive regulation of lymphocyte differentiation IMP
IMP: 通过突变表型推断
9620849 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

SH2 domain-containing inositol 5'-phosphatase 1

SH2 domain-containing inositol phosphatase 1

SH2-containing inositol phosphatase SHIP

Src homology 2 domain-containing inositol-5-phosphatase

inositol polyphosphate-5-phosphatase, 145 kDa

phosphatidylin

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS21142 Inpp5d Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS06829 INPP5D Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27659 Inpp5d Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Inpp5d NCBI NCBI:3635
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