2. Gene
  3. Krt2 - keratin 2 Gene

Krt2 - keratin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Krt2e; Krt2-2; Krt2-17

基因 ID: 16681 | 基因类型: protein coding

关于 Krt2

功能概要

Enables cytoskeletal protein binding activity. A structural constituent of skin epidermis. Involved in positive regulation of epidermis development. Acts upstream of or within intermediate filament organization and keratinocyte development. Located in keratin filament. Is expressed in several structures, including gut; male reproductive gland or organ; nervous system; neural retina; and vagina. Used to study bullous congenital ichthyosiform erythroderma. Human ortholog(s) of this gene implicated in bullous congenital ichthyosiform erythroderma and ichthyosis. Orthologous to human KRT2 (keratin 2). [provided by Alliance of Genome Resources, Apr 2022]

Krt2 基因产物(1)

mRNA Protein Name
NM_010668.2 NP_034798.2 keratin, type II cytoskeletal 2 epidermal
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cytoskeletal protein binding IMP
IMP: 通过突变表型推断
24751727 MGI
enables structural constituent of skin epidermis IMP
IMP: 通过突变表型推断
24751727 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within epidermis development IMP
IMP: 通过突变表型推断
24751727 MGI
acts upstream of or within intermediate filament organization IMP
IMP: 通过突变表型推断
24751727 MGI
acts upstream of or within keratinocyte development IMP
IMP: 通过突变表型推断
24751727 MGI
involved in positive regulation of epidermis development IMP
IMP: 通过突变表型推断
26603179 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
24751727 MGI
located in keratin filament IDA
IDA: 通过直接分析推断
24751727 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

keratin, type II cytoskeletal 2 epidermal

CK-2e

K2e

cytokeratin-2e

epithelial keratin-2e

keratin 2 epidermis

keratin complex 2, basic, gene 17

keratin complex 2, gene 17

keratin-2e

type-II keratin Kb2

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07443 KRT2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22215 Krt2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Krt2 NCBI NCBI:3849
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