1. Gene
  2. Psmb8 - proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) Gene

Psmb8 - proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) Gene

种属: Mus musculus

同用名: Lmp7; Lmp-7

基因 ID: 16913 | 基因类型: protein coding

关于 Psmb8

功能概要

Predicted to enable endopeptidase activity. Involved in fat cell differentiation. Acts upstream of or within antigen processing and presentation. Part of Proteasome core complex and spermatoproteasome complex. Is expressed in thymus primordium. Human ortholog(s) of this gene implicated in JMP syndrome. Orthologous to human PSMB8 (Proteasome 20S subunit beta 8). [provided by Alliance of Genome Resources, Apr 2022]

Psmb8 基因产物(1)

mRNA Protein Name
NM_010724.2 NP_034854.2 proteasome subunit beta type-8
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
31915251 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within antigen processing and presentation IMP
IMP: 通过突变表型推断
15356141 MGI
involved in fat cell differentiation IMP
IMP: 通过突变表型推断
21881205 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of proteasome core complex IDA
IDA: 通过直接分析推断
16857966 MGI
part of spermatoproteasome complex IDA
IDA: 通过直接分析推断
23706739 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

proteasome subunit beta type-8

MC13 (LMP7)

large multifunctional protease 7

low molecular mass protein 7

macropain subunit C13

multicatalytic endopeptidase complex subunit C13

proteasome component C13

proteasome subunit MC13

proteasome subunit beta-5i

proteosome (prosome, macro

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Psmb8 NCBI NCBI:5696