1. Gene
  2. Cblb - Cbl proto-oncogene B Gene

Cblb - Cbl proto-oncogene B Gene

种属: Rattus norvegicus

基因 ID: 171136 | 基因类型: protein coding

关于 Cblb

功能概要

Enables protein kinase binding activity. Involved in response to gravity; response to hormone; and signal transduction. Located in membrane raft. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and type 1 diabetes mellitus. Orthologous to human CBLB (Cbl proto-oncogene B). [provided by Alliance of Genome Resources, Apr 2022]

Cblb 基因产物(1)

mRNA Protein Name
NM_133601.1 NP_598285.1 E3 ubiquitin-protein ligase CBL-B
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
14531861 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hydrogen peroxide IEP
IEP: 通过表达模式推断
14715702 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
19546888 RGD
involved in response to gravity IEP
IEP: 通过表达模式推断
14715702 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
16984225 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase CBL-B

Cas-Br-M (murine) ecotropic retroviral transforming sequence b

Cas-Br-M (murine) ectropic retroviral transforming sequence b

Casitas B-lineage lymphoma b

Cbl proto-oncogene B, E3 ubiquitin protein ligase

Cbl proto-oncogene, E3 ubiquitin protein ligase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cblb NCBI NCBI:868