1. Gene
  2. Mtf1 - metal response element binding transcription factor 1 Gene

Mtf1 - metal response element binding transcription factor 1 Gene

种属: Mus musculus

同用名: MTF-1; Thyls

基因 ID: 17764 | 基因类型: protein coding

关于 Mtf1

功能概要

Enables DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and Histone Acetyltransferase binding activity. Involved in cellular response to zinc ion and transcription, DNA-templated. Acts upstream of or within positive regulation of transcription by RNA polymerase II; response to cadmium ion; and response to oxidative stress. Located in cytoplasm and nucleus. Is expressed in several structures, including brain; cardiovascular system; early conceptus; genitourinary system; and gut. Orthologous to human MTF1 (metal regulatory transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Mtf1 基因产物(1)

mRNA Protein Name
NM_008636.4 NP_032662.3 metal regulatory transcription factor 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
10952993 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
18605988 MGI
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
9582278 MGI
enables histone acetyltransferase binding IPI
IPI: 通过物理相互作用推断
18605988 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA-templated transcription IDA
IDA: 通过直接分析推断
24529376 MGI
acts upstream of cartilage homeostasis IMP
IMP: 通过突变表型推断
24529376 MGI
involved in cellular response to zinc ion IDA
IDA: 通过直接分析推断
24529376 MGI
acts upstream of or within positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
10952993 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9582278 MGI
acts upstream of or within response to cadmium ion IMP
IMP: 通过突变表型推断
9582278 MGI
acts upstream of or within response to oxidative stress IMP
IMP: 通过突变表型推断
9582278 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
24529376 MGI
located in nucleus IDA
IDA: 通过直接分析推断
24529376 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

metal regulatory transcription factor 1

MRE-binding transcription factor

metalloregulatory transcription factor

transcription factor MTF-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mtf1 NCBI NCBI:4520