2. Gene
  3. Mthfd2 - methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase Gene

Mthfd2 - methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NMDMC

基因 ID: 17768 | 基因类型: protein coding

关于 Mthfd2

功能概要

Predicted to enable several functions, including magnesium ion binding activity; methenyltetrahydrofolate cyclohydrolase activity; and methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity. Predicted to be involved in tetrahydrofolate interconversion. Predicted to act upstream of or within one-carbon metabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human MTHFD2 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase). [provided by Alliance of Genome Resources, Apr 2022]

Mthfd2 基因产物(1)

mRNA Protein Name
NM_008638.2 NP_032664.1 bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables methenyltetrahydrofolate cyclohydrolase activity IDA
IDA: 通过直接分析推断
2647744 MGI
enables methylenetetrahydrofolate dehydrogenase (NAD+) activity IDA
IDA: 通过直接分析推断
2647744 MGI
enables methylenetetrahydrofolate dehydrogenase (NADP+) activity IDA
IDA: 通过直接分析推断
2647744 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial

相关产品

Pre-clinical Phase
生物活性分子 (16)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-130251 DS18561882 99.87% 否
HY-101943 LY 345899 98.0% 否
HY-155950 TH9619 99.33% 否
HY-131943 DS44960156 ≥99.0% 否
HY-149825 MTHFD2-IN-1 Inhibitor / 否
HY-149826 MTHFD2-IN-2 Inhibitor / 否
HY-149827 MTHFD2-IN-3 Inhibitor / 否
HY-149828 MTHFD2-IN-4 Inhibitor / 否
HY-149828A MTHFD2-IN-4 sodium Inhibitor / 否
HY-155219 TH9028 Inhibitor / 否
HY-170361 MTHFD2-IN-5 Inhibitor / 否
HY-172910 MTHFD2-IN-6 Inhibitor / 否
HY-RS08776 MTHFD2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08777 MTHFD2L Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16648 Mthfd2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23082 Mthfd2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mthfd2 NCBI NCBI:10797
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