2. Gene
  3. Muc2 - mucin 2 Gene

Muc2 - mucin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MCM; wnn; 2010015E03Rik

基因 ID: 17831 | 基因类型: protein coding

关于 Muc2

功能概要

Predicted to enable identical protein binding activity. Acts upstream of or within several processes, including epithelial cell development; negative regulation of cell migration; and positive regulation of apoptotic process. Located in extracellular matrix; inner mucus layer; and outer mucus layer. Is expressed in ileum and intestine. Used to study inflammatory bowel disease. Human ortholog(s) of this gene implicated in asthma. Orthologous to human MUC2 (Mucin 2, oligomeric mucus/gel-forming). [provided by Alliance of Genome Resources, Apr 2022]

Muc2 基因产物(1)

mRNA Protein Name
NM_023566.4 NP_076055.4 mucin-2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables extracellular matrix structural constituent IDA
IDA: 通过直接分析推断
35337837 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19411636 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within apoptotic process IMP
IMP: 通过突变表型推断
11872843 MGI
acts upstream of or within glandular epithelial cell development IMP
IMP: 通过突变表型推断
11872843 MGI
involved in host-mediated regulation of intestinal microbiota composition IDA
IDA: 通过直接分析推断
33093110 MGI
involved in maintenance of gastrointestinal epithelium IDA
IDA: 通过直接分析推断
33093110 MGI
involved in mucus secretion IDA
IDA: 通过直接分析推断
35337837 MGI
acts upstream of or within negative regulation of cell migration IMP
IMP: 通过突变表型推断
11872843 MGI
acts upstream of or within negative regulation of cell population proliferation IMP
IMP: 通过突变表型推断
11872843 MGI
acts upstream of or within positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
11872843 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular matrix IDA
IDA: 通过直接分析推断
11352827 MGI
located in inner mucus layer IDA
IDA: 通过直接分析推断
18806221 MGI
is active in mucus layer IDA
IDA: 通过直接分析推断
35337837 MGI
located in outer mucus layer IDA
IDA: 通过直接分析推断
18806221 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mucin-2

colonic mucin

secreted gel-forming mucin

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-E70562 Mucinase StcE Activator / 否
HY-158471 Core 1 O-glycan (C1) / 否
HY-RS08838 MUC2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18623 Muc2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25109 Muc2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Muc2 NCBI NCBI:4583
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