2. Gene
  3. Nfe2l1 - nuclear factor, erythroid derived 2,-like 1 Gene

Nfe2l1 - nuclear factor, erythroid derived 2,-like 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NRF1; Lcrf1; TCF11; LCR-F1; TCF-11

基因 ID: 18023 | 基因类型: protein coding

关于 Nfe2l1

功能概要

This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases from the use of NRF1 for this gene, NFE2L1, and for "nuclear respiratory factor 1" which has an official symbol of NRF1. [provided by RefSeq, Jul 2008]

Nfe2l1 基因产物(7)

mRNA Protein Name
NM_001130450.1 NP_001123922.1 endoplasmic reticulum membrane sensor NFE2L1 isoform 1
NM_001130451.1 NP_001123923.1 endoplasmic reticulum membrane sensor NFE2L1 isoform 2
NM_001130452.1 NP_001123924.1 endoplasmic reticulum membrane sensor NFE2L1 isoform 2
NM_001130453.1 NP_001123925.1 endoplasmic reticulum membrane sensor NFE2L1 isoform 3
NM_001130454.1 NP_001123926.1 endoplasmic reticulum membrane sensor NFE2L1 isoform 4
NM_001361682.1 NP_001348611.1 endoplasmic reticulum membrane sensor NFE2L1 isoform 5
NM_008686.3 NP_032712.2 endoplasmic reticulum membrane sensor NFE2L1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
10037736 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
22586274 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
29149604 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
10037736 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IMP
IMP: 通过突变表型推断
22586274 MGI
enables cholesterol binding IDA
IDA: 通过直接分析推断
29149604 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
25637874 MGI
enables promoter-specific chromatin binding IDA
IDA: 通过直接分析推断
25637874 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11342101 MGI
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
16581765 MGI
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
16581765 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell redox homeostasis IDA
IDA: 通过直接分析推断
10601325 MGI
acts upstream of or within cellular homeostasis IMP
IMP: 通过突变表型推断
29400713 MGI
involved in cellular response to cholesterol IDA
IDA: 通过直接分析推断
29149604 MGI
acts upstream of or within cellular response to cholesterol IMP
IMP: 通过突变表型推断
29149604 MGI
acts upstream of or within cellular response to cold IMP
IMP: 通过突变表型推断
29400713 MGI
acts upstream of or within cellular response to copper ion IMP
IMP: 通过突变表型推断
24462598 MGI
involved in cellular response to oxidative stress IDA
IDA: 通过直接分析推断
10601325 MGI
involved in cholesterol homeostasis IDA
IDA: 通过直接分析推断
29149604 MGI
acts upstream of or within cholesterol homeostasis IMP
IMP: 通过突变表型推断
29149604 MGI
acts upstream of or within cysteine transport IMP
IMP: 通过突变表型推断
25092871 MGI
acts upstream of or within erythrocyte differentiation IMP
IMP: 通过突变表型推断
9501099 MGI
acts upstream of or within fructose 6-phosphate metabolic process IMP
IMP: 通过突变表型推断
25041126 MGI
acts upstream of or within glial cell fate commitment IDA
IDA: 通过直接分析推断
23840004 MGI
acts upstream of or within glucose 6-phosphate metabolic process IMP
IMP: 通过突变表型推断
25041126 MGI
acts upstream of or within glutathione metabolic process IMP
IMP: 通过突变表型推断
25092871 MGI
involved in lipid homeostasis IMP
IMP: 通过突变表型推断
22586274 MGI
acts upstream of or within mitotic metaphase IMP
IMP: 通过突变表型推断
22971132 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
10037736 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
24462598 MGI
acts upstream of or within protein polyubiquitination IMP
IMP: 通过突变表型推断
21554501 MGI
acts upstream of or within regulation of fatty acid metabolic process IMP
IMP: 通过突变表型推断
25092871 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
25041126 MGI
acts upstream of or within regulation of glucose metabolic process IMP
IMP: 通过突变表型推断
25041126 MGI
acts upstream of or within regulation of inflammatory response IMP
IMP: 通过突变表型推断
29149604 MGI
acts upstream of or within regulation of lipid metabolic process IMP
IMP: 通过突变表型推断
25092871 MGI
acts upstream of or within regulation of mitotic nuclear division IMP
IMP: 通过突变表型推断
22971132 MGI
acts upstream of or within regulation of nucleus organization IMP
IMP: 通过突变表型推断
22971132 MGI
acts upstream of or within regulation of proteasomal protein catabolic process IMP
IMP: 通过突变表型推断
27920251 MGI
acts upstream of or within regulation of response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
29400713 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
25637874 MGI
involved in regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
20385086 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
22971132 MGI
acts upstream of or within response to endoplasmic reticulum stress IDA
IDA: 通过直接分析推断
25637874 MGI
acts upstream of or within response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
23702335 MGI
acts upstream of or within spinal cord motor neuron differentiation IMP
IMP: 通过突变表型推断
21554501 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
29400713 MGI
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
25290918 MGI
located in nucleus IDA
IDA: 通过直接分析推断
29149604 MGI
part of protein-containing complex IDA
IDA: 通过直接分析推断
16581765 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

endoplasmic reticulum membrane sensor NFE2L1

NF-E2-related factor 1

NFE2-related factor 1

locus control region-factor 1

nuclear factor erythroid 2-related factor 1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-178997 NFE2L1 activator-1 / 否
HY-RS09244 NFE2L1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21165 Nfe2l1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27681 Nfe2l1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nfe2l1 NCBI NCBI:4779
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