2. Gene
  3. Ntf3 - neurotrophin 3 Gene

Ntf3 - neurotrophin 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Nt3; HDNF; NGF-2; Ntf-3

基因 ID: 18205 | 基因类型: protein coding

关于 Ntf3

功能概要

This gene encodes a member of the neurotrophins that have a wide variety of functions in both neural and non-neural tissues. The encoded preproprotein undergoes proteolytic processing to generate a noncovalently linked homodimeric mature protein that can bind to the transmembrane Receptor Tyrosine Kinases to initiate a series of signaling events. Mice lacking the encoded protein exhibit severe defects in the peripheral nervous system including a complete lack of spinal proprioceptive afferents and their peripheral sense organs. [provided by RefSeq, Sep 2016]

Ntf3 基因产物(5)

mRNA Protein Name
NM_001164034.2 NP_001157506.1 neurotrophin-3 isoform a
NM_001164035.2 NP_001157507.1 neurotrophin-3 isoform a
NM_001410128.1 NP_001397057.1 neurotrophin-3 isoform b preproprotein
NM_001410129.1 NP_001397058.1 neurotrophin-3 isoform c
NM_008742.4 NP_032768.1 neurotrophin-3 isoform b preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11684666 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within axon guidance IDA
IDA: 通过直接分析推断
15550985 MGI
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
8861722 MGI
acts upstream of or within brain development IMP
IMP: 通过突变表型推断
10195193 MGI
acts upstream of or within enteric nervous system development IMP
IMP: 通过突变表型推断
15497153 MGI
acts upstream of or within epidermis development IMP
IMP: 通过突变表型推断
9736028 MGI
acts upstream of or within generation of neurons IGI
IGI: 通过遗传相互作用推断
16142215 MGI
acts upstream of or within glial cell fate determination IMP
IMP: 通过突变表型推断
10384880 MGI
acts upstream of or within mechanoreceptor differentiation IGI
IGI: 通过遗传相互作用推断
15376326 MGI
acts upstream of or within negative regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
19915564 MGI
acts upstream of or within nerve development IMP
IMP: 通过突变表型推断
7605630 MGI
acts upstream of or within neuromuscular synaptic transmission IDA
IDA: 通过直接分析推断
11978828 MGI
acts upstream of neuron apoptotic process IMP
IMP: 通过突变表型推断
19915564 MGI
acts upstream of or within neuron development IMP
IMP: 通过突变表型推断
8809809 MGI
acts upstream of or within peripheral nervous system development IMP
IMP: 通过突变表型推断
8630254 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12741988 MGI
acts upstream of or within regulation of neuron apoptotic process IDA
IDA: 通过直接分析推断
16516892 MGI
acts upstream of or within smooth muscle cell differentiation IMP
IMP: 通过突变表型推断
15497153 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
14715936 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neurotrophin-3

nerve growth factor 2

neurotrophic factor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09616 NTF3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20313 Ntf3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26821 Ntf3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ntf3 NCBI NCBI:4908
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