2. Gene
  3. Phb - prohibitin Gene

Phb - prohibitin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Phb1; Bap32

基因 ID: 18673 | 基因类型: protein coding

关于 Phb

功能概要

Enables transcription corepressor activity. Involved in several processes, including CD40 signaling pathway; activation of Phospholipase C activity; and positive regulation of macromolecule metabolic process. Acts upstream of or within DNA biosynthetic process and negative regulation of transcription by RNA polymerase II. Located in several cellular components, including cell surface; mitochondrial inner membrane; and nucleus. Is expressed in ectoplacental cone; embryo; and extraembryonic ectoderm. Human ortholog(s) of this gene implicated in breast Cancer and sporadic breast Cancer. Orthologous to human PHB (prohibitin). [provided by Alliance of Genome Resources, Apr 2022]

Phb 基因产物(1)

mRNA Protein Name
NM_008831.4 NP_032857.1 prohibitin 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20959514 MGI
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
18480465 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in B cell activation IDA
IDA: 通过直接分析推断
23241883 MGI
acts upstream of or within DNA biosynthetic process IMP
IMP: 通过突变表型推断
18480465 MGI
involved in modulation by host of viral RNA genome replication IDA
IDA: 通过直接分析推断
29324904 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
18480465 MGI
involved in positive regulation of immunoglobulin production IDA
IDA: 通过直接分析推断
23241883 MGI
involved in positive regulation of non-canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
23241883 MGI
involved in symbiont entry into host cell IDA
IDA: 通过直接分析推断
29324904 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
22417827 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
29324904 MGI
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
20959514 MGI
part of mitochondrial prohibitin complex IPI
IPI: 通过物理相互作用推断
20959514 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
11884367 MGI
located in nucleus IDA
IDA: 通过直接分析推断
18480465 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
29324904 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prohibitin 1

B-cell receptor-associated protein 32

相关产品

Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-114989 Fluorizoline Inducer 99.77% 否
HY-152093 YL-939 Inhibitor 99.03% 否
HY-117113 JI051 Inhibitor 98.0% 否
HY-124484 JI130 Inhibitor 99.41% 否
HY-162904 BPU17 98.16% 否
HY-RS16807 Phb2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-141475 Acetoacetyl coenzyme A sodium / 否
HY-179574 AURKA-IN-4 Inhibitor / 否
HY-RS10407 PHB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS10408 PHB2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17295 Phb1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23247 Phb2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23750 Phb1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca fascicularis Phb NCBI
Rattus norvegicus Phb NCBI
Macaca mulatta Phb NCBI
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