Plod1 - procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 Gene

种属: Mus musculus

同用名: Lh1; Plod; 2410042F05Rik

关于 Plod1

功能概要

Predicted to enable several functions, including L-ascorbic acid binding activity; ferrous iron binding activity; and procollagen-lysine 5-dioxygenase activity. Predicted to be involved in epidermis development and peptidyl-lysine hydroxylation. Located in collagen-containing extracellular matrix. Part of catalytic complex. Is expressed in several structures, including alimentary system; brain; integumental system; sensory organ; and skeleton. Used to study Ehlers-Danlos syndrome. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome kyphoscoliotic type 1. Orthologous to human PLOD1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1). [provided by Alliance of Genome Resources, Apr 2022]