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  3. Pou2f2 - POU domain, class 2, transcription factor 2 Gene

Pou2f2 - POU domain, class 2, transcription factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Otf2; Oct-2; Oct2a; Oct2b; Oct2c; Oct2d; Otf-2

基因 ID: 18987 | 基因类型: protein coding

关于 Pou2f2

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein domain specific binding activity. Involved in cellular response to virus; positive regulation of interleukin-6 production; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within cell maturation; mature B cell differentiation; and positive regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including embryo mesenchyme; genitourinary system; nervous system; sensory organ; and thymus. Orthologous to human POU2F2 (POU class 2 homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Pou2f2 基因产物(4)

mRNA Protein Name
NM_001163554.1 NP_001157026.1 POU domain, class 2, transcription factor 2 isoform 4
NM_001163555.1 NP_001157027.1 POU domain, class 2, transcription factor 2 isoform 3
NM_001163556.1 NP_001157028.1 POU domain, class 2, transcription factor 2 isoform 1
NM_011138.2 NP_035268.2 POU domain, class 2, transcription factor 2 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
11937630 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
11937630 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
11937630 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11937630 MGI
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
7720710 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
7720710 MGI
enables spermidine transmembrane transporter activity IDA
IDA: 通过直接分析推断
23458604 MGI
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
23045607 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell maturation IMP
IMP: 通过突变表型推断
14978099 MGI
involved in cellular response to virus IMP
IMP: 通过突变表型推断
23045607 MGI
acts upstream of or within immunoglobulin production IMP
IMP: 通过突变表型推断
14978099 MGI
acts upstream of or within immunoglobulin production involved in immunoglobulin-mediated immune response IMP
IMP: 通过突变表型推断
8096198 MGI
acts upstream of or within mature B cell differentiation IMP
IMP: 通过突变表型推断
8096198 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
11937630 MGI
involved in positive regulation of interleukin-6 production IDA
IDA: 通过直接分析推断
23045607 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11937630 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
14978099 MGI
involved in spermidine transport IDA
IDA: 通过直接分析推断
23458604 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
11937630 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

POU domain, class 2, transcription factor 2

lymphoid-restricted immunoglobulin octamer-binding protein NF-A2

octamer-binding protein 2

octamer-binding transcription factor 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10898 POU2F2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20583 Pou2f2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27091 Pou2f2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pou2f2 NCBI NCBI:5452
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