1. Gene
  2. Pspn - persephin Gene

Pspn - persephin Gene

种属: Mus musculus

同用名: PSP

基因 ID: 19197 | 基因类型: protein coding

关于 Pspn

功能概要

This gene encodes a secreted ligand of the GDNF (glial cell line-derived neurotrophic factor) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. This protein may play a role in cell death, and nervous system development and function. Mice lacking a functional copy of this gene exhibit hypersensitivity to cerebral ischemia. [provided by RefSeq, Aug 2016]

Pspn 基因产物(1)

mRNA Protein Name
NM_008954.4 NP_032980.2 persephin preproprotein
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within branching involved in ureteric bud morphogenesis IDA
IDA: 通过直接分析推断
9491986 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
9491986 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

persephin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pspn NCBI NCBI:5623