1. Gene
  2. Rheb - Ras homolog enriched in brain Gene

Rheb - Ras homolog enriched in brain Gene

种属: Mus musculus

同用名: Rheb1

基因 ID: 19744 | 基因类型: protein coding

关于 Rheb

功能概要

Enables GTP binding activity and protein kinase binding activity. Involved in negative regulation of cold-induced thermogenesis and positive regulation of TOR signaling. Acts upstream of or within positive regulation of oligodendrocyte differentiation. Part of spliceosomal complex. Is expressed in chondrocranium bone; nervous system; nucleus pulposus; and sensory organ. Orthologous to human RHEB (Ras homolog, mTORC1 binding). [provided by Alliance of Genome Resources, Apr 2022]

Rheb 基因产物(1)

mRNA Protein Name
NM_053075.3 NP_444305.2 GTP-binding protein Rheb
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTP binding IDA
IDA: 通过直接分析推断
21336308 MGI
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
21336308 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
28242620 MGI
acts upstream of oligodendrocyte differentiation IMP
IMP: 通过突变表型推断
25411504 MGI
involved in positive regulation of TOR signaling IDA
IDA: 通过直接分析推断
21336308 MGI
involved in positive regulation of TORC1 signaling IDA
IDA: 通过直接分析推断
12820960 MGI
involved in positive regulation of TORC1 signaling IMP
IMP: 通过突变表型推断
21321084 MGI
acts upstream of or within positive regulation of oligodendrocyte differentiation IMP
IMP: 通过突变表型推断
25411504 MGI
involved in regulation of TOR signaling IMP
IMP: 通过突变表型推断
19258434 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Golgi membrane IDA
IDA: 通过直接分析推断
16631613 MGI
is active in endomembrane system IDA
IDA: 通过直接分析推断
16631613 MGI
part of spliceosomal complex IDA
IDA: 通过直接分析推断
11555636 MGI
is active in synapse EXP
EXP: 通过实验结果推断
25211037 MGI
is active in synapse IDA
IDA: 通过直接分析推断
25211037 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

GTP-binding protein Rheb

RAS-homolog enriched in brain

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rheb NCBI NCBI:6009